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Carmina Micelli

I am an enthusiastic second year PhD student supported by BBSRC and enrolled in the Bioenergy and Industrial Biotechnology theme of MIBTP.

Currently, I am working on an exciting project in the field of antimicrobial resistance (AMR), under the supervision of Dr. David Roper and Prof. Christopher Dowson at the University of Warwick. The project seeks to structurally and kinetically characterize a group of essential enzymes known as Penicillin-binding proteins (PBPs), involved in the last stages of the bacterial peptidoglycan biosynthetic pathway, and considered to be valuable targets for the development of new antibiotics. The project will provide the AMR community with new data on class A PBPs from the nosocomial infection pathogens Pseudomonas aeruginosa and Acinetobacter baumannii, that will aid the discovery of new compounds active against the increasing number of multi-drug resistant isolates.