Dr Stephane Gross
Supervisor Details
Research Interests
The research in our laboratory aims to characterise the role, at the cellular level, of different actin binding/bundling proteins on the organisation of the actin cytoskeleton and the potential roles these proteins may have in disease progressions, such as cancer and complicated pregnancies.
Our recent work focuses on proteins that have been linked to cancer progression and have been shown to enhance cellular migration, leading to a metastatic phenotype when it is over expressed in certain tumour cells.We have also now focused on deciphering the more physiological functions of these proteins in the context of healthy living and try to understand more about their roles in normal lives.
Our work and that of others has shown that both S100P and S100A4 affect the actin cytoskeleton though interaction with the non muscle myosin network. Using cell culture and state of the art facilities in cellular biology and molecular biology, we aim to understand the molecular mechanisms that allow these S100 proteins to remodel the actin cytoskeleton and the consequences of such reorganisation on cell migration. and mammalian systems as well asin vitrousing the state of the art facilities in cellular biology and molecular biology offered in our department.
Scientific Inspiration
Prof Neil Ron Morris (https://www.researchgate.net/profile/Nils-Morris). A person who dedicated his life to science and achieved much more than I can ever dream to. I was fortunate enough to work with him for a few months and appreciated his aptitude and helpfulness, his door always open and him always being available to support you whenever you needed help, regardless of his other commitments.
MIBTP Project Details
Current Projects (2025-26)
Primary supervisor for: