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Lymphatic Filariasis

Lymphatic Filariasis (LF) or elephantiasis is a neglected tropical disease caused by infection with three species of parasite: W. bancrofti, B. malayi and B. timori. The parasites nest in the lymphatic system and in the long-term lead to abonormal enlargement of body parts causing pain and severe disability. Currently over 120 million people are infected primarily in the following countries: Bangladesh, Côte d’Ivoire, Democratic Republic of Congo, India, Indonesia, Myanmar, Nigeria, Nepal, Philippines and the United Republic of Tanzania.

Currently there are global efforts to eliminate LF by 2020 through the use of annual of mass drug administration. There are important questions however in whether elimination can be achieved in regions of medium to high endemicity with mass drug administration alone and how certain factors of the mosquito vector biology and human behaviour may affect elimination as well as the risk of recrudesence.



Deirdre Hollingsworth

Mike Irvine

Lisa Reimer (LSTM)