The latest Orbital newsletter
Cancer targeted with reusable ‘stinging nettle’ treatment
Nature Chemistry has recently published research, led by Professor Peter Sadler, that has developed a new line of attack against cancer: an organic-osmium compound, which is triggered using a non-toxic dose of sodium formate, a natural product found in many organisms, including nettles and ants.
Named JPC11, it targets a metabolic process which cancer cells rely on to survive and multiply. It does this by converting a key substance used by cancer cells to provide the energy they need for rapid division (pyruvate) into an unnatural lactate - leading to the cells’ destruction.
For the full press release see here.
More electronic materials opened up with new metal-organic framework
Research published today in Nature Communications shows how high photoconductivity and semiconductor behaviour can be added to MOFs - which already have a huge international focus for their applications in gas storage, sensing and catalysis.
The new work, conducted by Universities in Brazil, the United Kingdom and France – including researchers at Warwick’s Department of Chemistry - found that the new MOF has a photoresponsivity of 2.5 × 105 A.W-1
The work has been highlighted in a press release.
Retarding oxidation of copper nanoparticles without electrical isolation, and the size dependence of work function
Research led by the Hatton group in collaboration with researchers from Warwick Physics, published in Nature Communications, advances the possibility of using copper nanoparticles for emerging electronic devices in place of more costly silver and gold nanoparticles.
The full open access article can be found here:
Figure shows a high resolution transmission electron microscope image of a ligand capped copper nanoparticle, showing the crystal lattice and individual copper atoms surrounding the nanoparticle.
Photoactive Iridium Complexes for Cancer Therapy
For the full article in ChemistryViews.org, see below:
Warwick Chemistry graduate invents revolutionary device for testing drugs
Dr Gabit Nurumbetov, Principal Scientist at Medherant Ltd - a spin-out of the University of Warwick which produces next-generation drug delivery patches - has invented a revolutionary device for testing transdermal drugs more quickly, efficiently and accurately. Dr Nurumbetov completed his PhD in the Department of Chemistry with Professor Stefan Bon then worked as a postdoctoral researcher in Professor David Haddleton’s group.