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News @ Warwick Chemistry

All events shown in the Department Calendar including the Departmental Seminar Programme.

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Chemistry World Today highlights Shipman Group Research

Chemistry World Today highlights Shipman Group Research into 'Synthetic strategy exploits fluxional nitrogen to deliver three chiral centres for the price of one'

https://www.chemistryworld.com/news/synthetic-strategy-exploits-fluxional-nitrogen-to-deliver-three-chiral-centres-for-the-price-of-one/4011029.article

Tue 21 Jan 2020, 18:49 | Tags: SynthCat Research news

Alzheimer's discovery published in Science Advances

Peptide-mimetic metallohelices bind Alzheimer protein and extend life in an insect model

Sun 21 Jan 2018, 12:58 | Tags: news publications SynthCat ChemBio

Scott, Fox and Gibson develop 'metallohelical antifreezes'

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A collaboration between the Fox, Scott and Gibson groups has been published in the Journal of the American Chemical Society. The team were inspired by how small helical antifreeze proteins in Nature enable extreomophiles to survive low temperatures, where other species would not survive. Rather than using traditional peptide/protein chemistry, the team used self-assembled metallohelicates which have similar dimensions to a small alpha helix, and found some which were remarkably potent at stopping ice crystal growth ; a major technological challenge in applications from wind farms, to aircraft to cryopreservation. Modelling studies showed that the underlying activity could be linked the patches of hydrophobicity (water liking) and hydrophobicity (water hating).

Read the paper here

Antifreeze Protein Mimetic Metallohelices with Potent Ice Recrystallization Inhibition Activity

Thu 10 Aug 2017, 07:57 | Tags: PolymerChem publications SynthCat MeasMod


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