1. Asawin Likhitsup, Robert J Deeth, Sijbren Otto, Andrew Marsh "Apparent non-statistical binding in a ditopic receptor for guanosine",
Organic & Biomolecular Chemistry, 2009, DOI: 10.1039/B812969j
The following are MS Excel spreadsheets that enable curve fitting of NMR titration data and calculation of probabilities of binding for molecules above. Monoalkyne is receptor 1, dialkyne is receptor 2, guanosine is guest 3.
Excel Spreadsheet 1: Curve fitting for dilution of monoalkyne receptor 1 (dimer).
Excel Spreadsheet 2: Curve fitting for dilution of dialkyne receptor 2 (dimer).
Excel Spreadsheet 3: Curve fitting for dilution of guanosine guest 3 (G dimer and G tetramer).
Excel Spreadsheet 4: Global curve fitting for 2:1 complex 3•1•3 assuming receptor dimer and guanosine tetramer.
Excel Spreadsheet 5: Global curve fitting for 2:1 complex 3•2•3 assuming receptor dimer and guanosine tetramer.
You can also find PDF files of Supporting Information here including methods used for NMR and ITC titrations and analysis: