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Efficient polymer and nanostructure modification


The development of robust chemistries for the modification of polymers and their assemlbed constructs is a key underpinning technology which is of interest to the O'Reilly group. We explore the application of novel efficient and effective chemistries for the funcitonalisation and modification of a range of polymer scaffolds to enable;

- orthogonal chemical functionalisation

- end group and/or side chain modification

- efficient conjugation of polymers, biomolecules and small molecules such as actives and catalysts

Selected Publications

Amphiphilic Block Copolymer Self-Assemblies of Poly(NVP)-b-poly(MDO-co-vinyl esters): Tunable Dimensions and Functionalities, G. G. Hedir, A. Pitto-Barry, A. P. Dove, R.K.O'Reilly, J. Polym. Sci. Part A: Polym. Chem, 2015, 53, 2699-2710, DOI: 10.1002/pola.27915


Orthogonal Modification of Norbornene-Functional Degradable Polymers, R. J. WIlliams, I. Barker, R.K. O'Reilly and A.P. Dove, ACS Macro Letters 2012, 1285-1290. DOI: 10.1021/mz300496q


Dibromomaleimide end functional polymers by RAFT polymerization without the need of protecting groups, M. Robin, M. Jones, D.M. Haddleton, R.K. O'Reilly, ACS Macro Lett., 2012, 1, 222-226. DOI: 10.1021/mz200164x


Additive-free Clicking for Polymer Functionalization and Coupling by Tetrazine-Norbornene Chemistry, C. F. Hansell, P. Espeel, M. M. Stamenovic, I. A. Barker, A. P. Dove, F. E. Du Prez, R. K. O’Reilly, J. Am. Chem. Soc., 2011, 133, 13828-13831. DOI: 10.1021/ja203957h