Leverhulme Trust Early Career Fellow (Senior Research Fellow)
Fabrizio holds a joint appointment between the Department of Chemistry and the School of Life Sciences, and he is the recipient of a Leverhulme Trust Early Career Fellowship. Before starting his independent research, he was a Postdoctoral Research Fellow in the Corre Lab (2015-2018), working to discover new natural products from actinomycetes.
He completed his Ph.D. studies at the University of Bristol in the Foster/Bailey Lab (2012-2015), focusing on the biosynthesis of terpenoid antibiotics. He graduated from the University of Perugia (Italy) with a BSc and MSc in Biotechnology.
Groups at Warwick
- Member of the Chemical Biology Research Facility (CBRF).
- Member of the Biotechnology Research Theme in the School of Life Sciences.
- 2018 - present, Leverhulme Trust Early Career Fellow, University of Warwick
- 2015 - 2018, Postdoctoral Research Fellow, University of Warwick
- 2012 - 2015, PhD in Microbiology/Chemical Biology, University of Bristol
- 2009 - 2012, MSc in Environmental Biotechnology, University of Perugia (Italy)
- 2006 - 2009, BSc in Biotechnology, University of Perugia (Italy)
I am working on the following projects at the moment:
- refactoring the biosynthesis of terpenoid natural products from fungi,
- discovering bioactive natural products from actinomycete bacteria.
I am currently interested in the characterisation of bioactive natural products made by microorganism.
The main aims of my research are:
- to refactor the biosynthesis of terpenoid natural products from fungi,
- to discover bioactive natural products from actinomycete bacteria.
I am supervising the following PhD students:
- Mr Jack Weaver, biosynthesis of terpenoid natural products in fungi (jointly supervised with Dr Chris Corre).
- Ms Duha Alkhder, mode of action of stilbene antibiotics (jointly supervised with Dr Nick Waterfield, WMS).
- Ms Marlene Rothe (jointly supervised with Prof Greg Challis).
(* corresponding author(s); § joint authors)
- Kaur, Divjot, Corre, Christophe, Alberti, Fabrizio*, 2020, Engineering isoprenoid quinone production in yeast. BioRxiv 2020-932020v1, doi: https://doi.org/10.1101/2020.02.06.932020.
- Alberti, Fabrizio*, Leng, Daniel J., Wilkening, Ina, Song, Lijiang, Tosin, Manuela, Corre, Christophe*, 2019. Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery. Chemical Science, 10 (2), pp. 453-463.
- Alberti, Fabrizio, Corre, Christophe, 2019. Editing streptomycete genomes in the CRISPR/Cas9 age. Natural Product Reports, 36 (9), pp. 1237-1248.
- Alberti, Fabrizio, Khairudin, Khairunisa, Venegas, Edith Rodriguez, Davies, Jonathan A., Hayes, Patrick M., Willis, Christine L., Bailey, Andy M.*, Foster, Gary D.*, 2017. Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives. Nature Communications, 8 (1), 1831.
- Alberti, Fabrizio*, Foster, Gary D., Bailey, Andy M., 2017. Natural products from filamentous fungi and production by heterologous expression. Applied Microbiology and Biotechnology, 101 (2), pp. 493-500.
- Bailey, Andy M.§, Alberti, Fabrizio§, Kilaru, Sreedhar§, Collins, Catherine M.§, de Mattos-Shipley, Kate§, Hartley, Amanda J., Hayes, Patrick, Griffin, Alison, Lazarus, Colin M., Cox, Russell J., Willis, Christine L., O'Dwyer, Karen, Spence, David W., Foster, Gary D., 2016. Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production. Scientific Reports, 6 (1), 25202.
- de Mattos-Shipley, K. M. J., Ford, K. L., Alberti, Fabrizio, Banks, A. M., Bailey, A. M., Foster, G. D.*, 2016. The good, the bad and the tasty : the many roles of mushrooms. Studies in Mycology, 85, pp. 125-157.
- Alberti, Fabrizio*, 2016. Current trends in natural products research from the CBNP10 Symposium at Warwick. Exchanges: the Interdisciplinary Research Journal, 4 (1), pp. 158-166.