Job Title
UKRI Future Leaders Fellow
Department
Life Sciences
Email
Web Link
Research Interests
I am interested in the characterisation of bioactive natural products made by microorganisms.
The main aims of my research are:
- to develop synthetic biology tools for the engineering of fungi
- to refactor the biosynthesis of terpenoid natural products from fungi
- to discover bioactive natural products from actinomycete bacteria.
For more information please visit Alberti lab
Biography
UKRI Future Leaders Fellow, University of Warwick (2022 - present)
Leverhulme Trust Early Career Fellow, University of Warwick (2018 - 2022)
Postdoctoral Research Fellow, University of Warwick (2015 - 2018)
PhD in Microbiology, University of Bristol (2012 - 2015)
- 'Paliwal, Deepa, 'Hamilton, Amanda J., 'Barrett, Glyn A., 'Alberti, Fabrizio, 'Emden, Helmut, 'Monteil, Caroline L., 'Mauchline, Tim H., 'Nauen, Ralf, 'Wagstaff, Carol, 'Bass, Chris, 'Jackson, Robert W., 2022. 'Identification of novel aphid?killing bacteria to protect plants. Microbial Biotechnology, 15 (4), pp. 1203-1220
- 'Tamizi, Amin-Asyraf, 'Mat-Amin, Noriha, 'Weaver, Jack, 'Olumakaiye, Richard T., 'Akbar, Muhamad Afiq, 'Jin, Sophie, 'Bunawan, Hamidun, 'Alberti, Fabrizio, 2022. 'Genome sequencing and analysis of Trichoderma (Hypocreaceae) isolates exhibiting antagonistic activity against the papaya dieback pathogen, Erwinia mallotivora. Journal of Fungi, 8 (3)
- Al-Salihi, Suhad A. A., Alberti, Fabrizio, 2021. Naturally occurring terpenes : a promising class of organic molecules to address influenza pandemics. Natural Products and Bioprospecting, 11, pp. 405-419
- Bugg, Tim, Williamson, James J., Alberti, Fabrizio, 2021. Microbial hosts for metabolic engineering of lignin bioconversion to renewable chemicals. Renewable and Sustainable Energy Reviews, 152
- Alberti, Fabrizio, Kaleem, Saraa, Weaver, Jack, 2020. Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research. Biology Open, 9 (12)
- Kaur, Divjot, Alkhder, Duha, Corre, Christophe, Alberti, Fabrizio, 2020. Engineering isoprenoid quinone production in yeast. ACS Synthetic Biology, 9 (9), pp. 2239-2245
- Alberti, Fabrizio, Leng, Daniel J., Wilkening, Ina, Song, Lijiang, Tosin, Manuela, Corre, Christophe, 2019. Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery. Chemical Science, 10 (2), pp. 453-463
- Alberti, Fabrizio, Corre, Christophe, 2019. Editing streptomycete genomes in the CRISPR/Cas9 age. Natural Product Reports, 36 (9), pp. 1237-1248
- Alberti, Fabrizio, Foster, Gary D., Bailey, Andy M., 2017. Natural products from filamentous fungi and production by heterologous expression. Applied Microbiology and Biotechnology, 101 (2), pp. 493-500
- Alberti, Fabrizio, Khairudin, Khairunisa, Venegas, Edith Rodriguez, Davies, Jonathan A., Hayes, Patrick M., Willis, Christine L., Bailey, Andy M., Foster, Gary D., 2017. Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives. Nature Communications, 8 (1)
- Bailey, Andy M., Alberti, Fabrizio, Kilaru, Sreedhar, Collins, Catherine M., de Mattos-Shipley, Kate, Hartley, Amanda J., Hayes, Patrick, Griffin, Alison, Lazarus, Colin M., Cox, Russell J., Willis, Christine L., O'Dwyer, Karen, Spence, David W., Foster, Gary D., 2016. Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production. Scientific Reports, 6 (1)
- de Mattos-Shipley, K. M. J., Ford, K. L., Alberti, Fabrizio, Banks, A. M., Bailey, A. M., Foster, G. D., 2016. The good, the bad and the tasty : the many roles of mushrooms. Studies in Mycology, 85, pp. 125-157
- Alberti, Fabrizio, 2016. Current trends in natural products research from the CBNP10 Symposium at Warwick. Exchanges: the Warwick Research Journal, 4 (1)
- 'Chhun, Audam, 'Alberti, Fabrizio, 2022. 'CRISPR/Cas9-based methods for inactivating actinobacterial biosynthetic genes and elucidating function. In Skellam, Elizabeth (ed.), Engineering Natural Product Biosynthesis, New York, Humana Press, pp. 201-222
| Title | Funder | Award start | Award end |
|---|---|---|---|
| Production of high-value chemicals in the button mushroom: a synthetic biology toolkit | UK Research and Innovation | 01 Feb 2022 | 31 Jan 2026 |
| BBSRC Mid-range Equipment ALERT 2021 Application - November 2021 | BBSRC | 01 Aug 2022 | 31 Jul 2023 |
| Early Career Fellowship costed extension for Dr Fabrizio Alberti (linked to Ideate 58035 Engineering a yeast cell factory for production of valuable meroterpenoids) | Leverhulme Trust | 01 Nov 2021 | 31 Jan 2022 |
| Engineering a yeast cell factory for production of valuable meroterpenoids. Early Career Fellowship for Dr Fabrizio Alberti | Leverhulme Trust | 01 Nov 2018 | 31 Oct 2021 |