I am a postdoctoral researcher in Life Science at Warwick working with Professor Matt Keeling and Professor Laura Green.
Our research project focuses on modelling footrot in the UK, a bacterial disease of sheep causing lesions and lameness spread. This has a considerable impact on animal welfare and on the UK farming industry. The causative agent of ovine footrot is Dichelobacter nodosus, an anaerobic bacterium that survives in the soil for a short time and that is found in healthy and diseased sheep feet. We are concentrating on studying D. nodosus and its relation to the dynamics of the disease at foot- and population-level.
Further information on this project can be found here.
My Phd, awarded February 2015, was in Systems Biology at Warwick, working on modelling the electrogenic transmembrane proteins in excitable. Our cell of interest was the myometrial smooth muscle cell (MSMC), which is the principal unit of electrical activity in the uterus. These cells are normally quiescent except prior to and during labour when spontaneous action potentials are generated by the cells. We presented a method that combines the cell mRNA expression data, together with native cell behaviour (biophysical data) to characterise the complete repertoire of electrogenic proteins that are potentially expressed the MSMCs.