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Dr Martin Kubes

 

Title   

Marie Curie Research Fellow
 

Contact   

Life Sciences
University of Warwick
Coventry
CV4 7AL
Email: Martin.Kubes@warwick.ac.uk
WebLink: CrysPINs

Research Interests

My main goal is to derive a model for the structure of PIN1 and 5 protein, and optionally other PIN proteins, using techniques of molecular biology, biochemistry and crystallography. Members of PIN family are plant-specific auxin transporters, which play crucial role in plant morphogenesis, development and responses to the environment. Although it is well known that PIN proteins drive polar auxin transport, till nowadays the auxin research community is missing detailed functional and mechanistic models of these enigmatic transporters.

My vision is that we will be able to develop a detailed molecular map of PINs together with associated pharmacophoric map for their substrates and inhibitors, a goal that will offer me an ideal system for further research focused on PINs auxin substrate specificity and transport capacity. On the way I will expect to reveal how the PINs are energized, and create links with the auxin herbicide industries to explore opportunities for collaborations on agro-pharmaceutical compound design.


Biography

DPhil, Plant Biology. Charles University in Prague, 2011
MSc, Plant Biology. Charles University in Prague, 2004
BSc, Biology and Ecology. University of Ostrava, 2001

Publications

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Research Themes

Plant & Crop Science