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Journals


  • Guy, Collette S., Gibson, Matthew I., Fullam, Elizabeth. 2019. Targeting extracellular glycans : tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis. Chemical Science, 10 (23), pp. 5935-5942, View
  • Fenn, Jonathan S., Nepravishta, Ridvan, Guy, Collette S., Harrison, James, Angulo, Jesus, Cameron, Alexander, Fullam, Elizabeth. 2019. Structural basis of glycerophosphodiester recognition by the mycobacterium tuberculosis substrate-binding protein UgpB. ACS Chemical Biology, 14 (9), pp. 1879-1887, View
  • Radhakrishnan, Anjana, Furze, Christopher M., Ahangar, Mohd Syed, Fullam, Elizabeth. 2018. A GFP-strategy for efficient recombinant protein overexpression and purification in Mycobacterium smegmatis. RSC Advances, 8 (58), pp. 33087-33095, View
  • Ahangar, Mohd Syed, Furze, Christopher M., Guy, Collette S., Cooper, Charlotte, Maskew, Kathryn S, Graham, Benjamin T., Cameron, Alexander, Fullam, Elizabeth. 2018. Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA). Journal of Biological Chemistry, 293 (25), pp. 9770-9783, View
  • Richards, Sarah-Jane, Isulfi, Klea, Wilkins, Laura E., Lipecki, Julia, Fullam, Elizabeth, Gibson, Matthew I.. 2017. Multivalent antimicrobial polymer nanoparticles target mycobacteria and gram-negative bacteria by distinct mechanisms. Biomacromolecules, 19 (1), pp. 256-264, View
  • Guy, Collette S., Tichauer, Esther, Kay, Gemma L., Phillips, Daniel J., Bailey, Trisha L., Harrison, James, Furze, Christopher M., Millard, Andrew D., Gibson, Matthew I., Pallen, Mark J., Fullam, Elizabeth. 2017. Identification of the anti-mycobacterial functional properties of piperidinol derivatives. British Journal of Pharmacology, 174 (14), pp. 2183-2193, View
  • Phillips, Daniel J., Harrison, James, Richards, Sarah-Jane, Mitchell, Daniel E., Tichauer, Esther, Hubbard, Alasdair T. M., Guy, Collette S., Hands-Portman, Ian, Fullam, Elizabeth, Gibson, Matthew I.. 2017. Evaluation of the antimicrobial activity of cationic polymers against mycobacteria : toward antitubercular macromolecules. Biomacromolecules, 18 (5), pp. 1592-1599, View
  • Fullam, Elizabeth, Prokes, Ivan, Fütterer, Klaus, Besra, Gurdyal S.. 2016. Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars. Open Biology (6), View
  • Otten, Lucienne, Fullam, Elizabeth, Gibson, Matthew I.. 2016. Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile. Molecular BioSystems, 12 (2), pp. 341-344, View
  • Lowery, Richard, Gibson, Matthew I., Thompson, Richard C., Fullam, Elizabeth. 2015. Deuterated carbohydrate probes as 'label-free' substrates for probing nutrient uptake in mycobacteria by nuclear reaction analysis. Chemical communications, 51 (23), pp. 4838-4841, View
  • Gibson, Matthew I., Neres, Jo ão, Fullam, Elizabeth. 2014. Selective detection of epimeric pentose saccharides at physiological pH using a fluorescent receptor. Carbohydrate research, Volume 391, pp. 61-65, View
  • Richards, Sarah-Jane, Fullam, Elizabeth, Besra, Gurdyal S., Gibson, Matthew I.. 2014. Discrimination between bacterial phenotypes using glyco-nanoparticles and the impact of polymer coating on detection readouts. Journal of Materials Chemistry B, Volume 2 (Number 11), pp. 1490-1498, View
  • Abuhammad, Areej, Fullam, Elizabeth, Bhakta, Sanjib, Russell, Angela, Morris, Garrett, Finn, Paul, Sim, Edith. 2014. Exploration of piperidinols as potential antitubercular agents. Molecules, Volume 19 (Number 10), pp. 16274-16290, View
  • Fullam, Elizabeth, Talbot, James, Abuhammed, Areej, Westwood, Isaac, Davies, Stephen G., Russell, Angela J., Sim, Edith. 2013. Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase. Bioorganic & Medicinal Chemistry Letters, Vol.23 (No.9), pp. 2759-2764, View
  • Otten, Lucienne, Richards, Sarah-Jane, Fullam, Elizabeth, Besra, Gurdyal S., Gibson, Matthew I.. 2013. Gold nanoparticle-linked analysis of carbohydrate-protein interactions, and polymeric inhibitors, using unlabelled proteins; easy measurements using a 'simple' digital camera. Journal of Materials Chemistry B, Volume 1 (Number 20), pp. 2665-2672, View
  • Neres, J., Pojer, F., Molteni, E., Chiarelli, L. R., Dhar, N., Boy-Rottger, S., Buroni, S., Fullam, Elizabeth, Degiacomi, G., Lucarelli, A. P., Read, R. J., Zanoni, G., Edmondson, D. E., De Rossi, E., Pasca, M. R., McKinney, J. D., Dyson, P. J., Riccardi, G., Mattevi, A., Cole, S. T., Binda, C.. 2012. Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis. Science Translational Medicine, Vol.4 (No.150), View
  • Abuhammad, Areej, Fullam, Elizabeth, Lowe, Edward D., Staunton, David, Kawamura, Akane, Westwood, Isaac, Bhakta, Sanjib, Garner, Alun Christopher, Wilson, David L., Seden, Peter T., Davies, Stephen G., Russell, Angela J., Garman, Elspeth F., Sim, Edith. 2012. Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages. PLoS One, Volume 7 (Number 12), View
  • Fullam, Elizabeth, Pojer, Florence, Bergfors, Terese, Jones, T. Alwyn, Cole, Stewart T.. 2012. Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme. Open Biology, Volume 2 (110026), View
  • Fullam, Elizabeth, Abuhammad, Areej, Wilson, David L., Anderton, Matthew C., Davies, Steve G., Russell, Angela J., Sim, Edith. 2011. Analysis of ß-amino alcohols as inhibitors of the potential anti-tubercular target N-acetyltransferase. Bioorganic & Medicinal Chemistry Letters, Volume 21 (Number 4), pp. 1185-90, View
  • Westwood, Isaac M., Bhakta, Sanjib, Russell, Angela J., Fullam, Elizabeth, Anderton, Matthew C., Kawamura, Akane, Mulvaney, Andrew W., Vickers, Richard J., Bhowruth, Veemal, Besra, Gurdyal S., Lalvani, Ajit, Davies, Stephen G., Sim, Edith. 2010. Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars.. Protein & Cell, Volume 1 (Number 1), pp. 82-95, View
  • Abuhammad, Areej M., Lowe, Edward D., Fullam, Elizabeth, Noble, Martin, Garman, Elspeth F., Sim, Edith. 2010. Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site. Protein & Cell, Volume 1 (Number 4), pp. 384-92, View
  • Fullam, Elizabeth, Kawamura, Akane, Wilkinson, Helen, Abuhammad, Areej, Westwood, Isaac, Sim, Edith. 2009. Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis. The Protein Journal, Volume 28 (Number 6), pp. 281-293, View
  • Makarov, Vadim, Manina, Giulia, Mikusova, Katarina, Möllmann, Ute, Ryabova, Olga, Saint-Joanis, Brigitte, Dhar, Neeraj, Pasca, Maria Rosalia, Buroni, Silvia, Lucarelli, Anna Paola, Milano, Anna, De Rossi, Edda, Belanova, Martina, Bobovska, Adela, Dianiskova, Petronela, Kordulakova, Jana, Sala, Claudia, Fullam, Elizabeth, Schneider, Patricia, McKinney, John D, Brodin, Priscille, Christophe, Thierry, Waddell, Simon, Butcher, Philip, Albrethsen, Jakob, Rosenkrands, Ida, Brosch, Roland, Nandi, Vrinda, Bharath, Sowmya, Gaonkar, Sheshagiri, Shandil, Radha K, Balasubramanian, Venkataraman, Balganesh, Tanjore, Tyagi, Sandeep, Grosset, Jacques, Riccardi, Giovanna, Cole, Stewart T. 2009. Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis. Science (New York, N.Y.), Volume 324 (Number 5928), pp. 801-804, View
  • Sandy, James, Holton, Simon, Fullam, Elizabeth, Sim, Edith, Noble, Martin. 2009. Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis. Protein science : a publication of the Protein Society, Volume 14 (Number 3), pp. 775-782, View
  • Lack, Nathan A, Kawamura, Akane, Fullam, Elizabeth, Laurieri, Nicola, Beard, Stacey, Russell, Angela J, Evangelopoulos, Dimitrios, Westwood, Isaac, Sim, Edith. 2008. Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis. The Biochemical journal, Volume 418 (Number 2), pp. 369-78, View
  • Sim, Edith, Lack, Nathan, Wang, Chan-Ju, Long, Hilary, Westwood, Isaac, Fullam, Elizabeth, Kawamura, Akane. 2008. Arylamine N-acetyltransferases : structural and functional implications of polymorphisms. Toxicology, Volume 254 (Number 3), pp. 170-83, View
  • Sim, Edith, Sandy, James, Evangelopoulos, Dimitrios, Fullam, Elizabeth, Bhakta, Sanjib, Westwood, Isaac, Krylova, Anna, Lack, Nathan, Noble, Martin. 2008. Arylamine N-acetyltransferases in mycobacteria. Current drug metabolism, Volume 9 (Number 6), pp. 510-519, View
  • Fullam, Elizabeth, Westwood, Isaac M., Anderton, Matthew C., Lowe, Edward D., Sim, Edith, Noble, Martin E. M.. 2007. Divergence of cofactor recognition across evolution : coenzyme A binding in a prokaryotic arylamine N-acetyltransferase. Journal of Molecular Biology, Volume 375 (Number 1), pp. 178-91, View
  • Sim, Edith, Westwood, Isaac, Fullam, Elizabeth. 2007. Arylamine N-acetyltransferases. Expert Opinion on Drug Metabolism & Toxicology, Volume 3 (Number 2), pp. 169-84, View
  • Westwood, I. M., Kawamura, A., Fullam, Elizabeth, Russell, A. J., Davies, S. G., Sim, E.. 2006. Structure and mechanism of arylamine N-acetyltransferases. Current topics in medicinal chemistry, Volume 6 (Number 15), pp. 1641-1654, View


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