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Proteomics Research Technology Platform

Welcome to the Proteomics Facility at the University of Warwick. We provide a full Proteomics Service to academic and commercial researchers seeking to identify and quantify proteins and their modifications. The analysis of protein mixtures from gel slices, co-immunoprecipitations or enrichments is routine and we can identify and quantify several thousand proteins in complex samples, for example from whole cell lysates or tissue extracts. You will find support from an enthusiastic proteomics team to help with scientific discussion, experimental design, sample preparation and analysis of mass spectrometry data.


Services
Proteomics Services

• Discussion and advice on experimental design and sample preparation for peptide-based mass spectrometry including enrichment strategies.

• Confirmation of protein identity, for example of recombinant proteins.

• Identification of protein interaction partners from co-immunoprecipitation experiments.

• Relative quantification of proteomes using label-free or stable isotope labelling (iTRAQ, TMT or SILAC).

• Analysis of protein modifications such as phosphorylation, acetylation or ubiquitination.


Instruments

Our proteomics core facility is equipped with state-of-the-art mass spectrometers and UPLC separation platforms for powerful LC-MS and LC-MS/MS.

Proteomics Instrumentation

Left: timsTOF PROLink opens in a new window ion mobility Q-ToF mass spectrometer with nanoElute UPLC (Bruker)

Centre: Orbitrap FusionLink opens in a new window with UltiMate 3000 RSLCnano System (Thermo Scientific)

Right: QuantivaLink opens in a new window triple quadrupole with UltiMate 3000 RSLCnano System (Thermo Scientific)


Charges

We provide a fee-based service for Warwick researchers and external clients. Please contact us to discuss your requirements and to calculate costs.

Costs for University of Warwick staff and students

External Clients should contact the laboratory manager to enquire about Project pricing. Contractual matters will be handled via Warwick Scientific ServicesLink opens in a new window.

Additional ways to access the Proteomics RTP:


Laboratory Access

i. the SLS General Laboratory InductionLink opens in a new window

ii. the SLS Waste Management Moodle courseLink opens in a new window

iii. the RTP Proteomics Laboratory Guidance FormLink opens in a new window .