Welcome to my e-portfolio!
I'm a final year PhD student in the Department of Life Sciences under the supervision of Prof. Robert Freedman. The Freedman group works on protein disulphide isomerases (PDI) which are ER-resident protein folding catalysts found in eukaroytic cells. My work specifically works on PDIp which is a pancreas-specific homolog of PDI with ~45% sequence identity. Currently very little is known about PDIp- which makes it very exciting territory. As a member of the structural biology group we wanted to study both the structure and binding specificity of this protein.
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