Deciphering how complex organ form emerges in development
Professor Timothy Saunders

Abstract: Our internal organs have specific three-dimensional morphologies essential for their efficient function. Defects in morphogenesis lead to diseases in adults – for example, over 40% of adult heart disease can be traced to a developmental context. Yet, we know remarkably little about the physical processes underlying internal organ morphogenesis. Here, I present quantitative analysis of early muscle formation in zebrafish. This system is highly accessibly to live imaging and is enabling us to decipher the biophysical mechanisms helping to build the first skeletal muscle structures. In particular, we explore how organogenesis can be so robust in the face of challenges during development.

Engagement to embed research in the NHS
Dr Harpal Randeva

Abstract: Clinical research is good for patients, the NHS and the economy. But in a health service under pressure, it’s often seen as important but not urgent. During this seminar I will explore how NHS staff contribute to research, the factors that enable engagement, the impact of engagement on outcomes, and the implications for future engagement efforts.