New insight into shifts in lipid composition with age in genetically identical male and female Daphnia with different lifespan and ageing rate
In this study, UHPLC-MS/MS lipidomics was used to measure the dynamic changes in lipid composition as a function of age and gender throughout the lifespan of genetically identical male and female D. magna. The collaborative study between Mirbahai and Viant groups demonstrated that more than half of all lipids measured, including triglycerides and diglycerides are statistically different between female and male D. magna with age. This study provides a benchmark dataset to enhance our understanding of the significant role of lipids in regulation of health and disease. DOI: 10.1038/s41598-020-62476-z.