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Actin and myosin organise hierarchically to avoid blocking each other and to allow aster formation

How can membrane bound actin and myosin motors form contractile platforms without being in each other's way? The solution lies in their self-organization into layers on top of each other. The collaboration between experiment (Mayor group and Koester) and modeling (Rao and Skrepnek groups) of minimal, membrane bound acto-myosin networks provided new insights into this phenomenon that is important for our understanding of the cell cortex dynamics in close proximity to the plasma membrane. DOI: 10.1126/sciadv.aay6093

Fri 13 Mar 2020, 09:36 | Tags: BMS