UK Clock Club Talk by Lauren
New research article in Scientific Reports on circadian Pgp expression and its importance for drug transporters
Co-lead author Swati A. Kumar in a collaboration with Annabelle Ballesta, Alper Okyar, Francis Lévi, Enza Piccolo and us entitled: Sex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling, we described how time-of-day of drug adminstration might lead to different pharmacokinetic profiles in male and female mice.
Alper Okyar, Swati Kumar, Elisabeth Filipski, Enza Piccolo, Narin Ozturk, Helena Xandri-Monje, Zeliha Pala, Kristin Abraham, Ana Rita Gato de Jesus Gomes, Mehmet N. Orman, Xiao-Mei Li, Robert Dallmann, Francis Lévi, Annabelle Ballesta, Scientific Reports, 2019, DOI: 10.1038/s41598-019-46977-0
If you want to know what circadian phase a tissue has, but your patient is only willing to get biopsied once and not 6 times in 24 hours: Use TimeTeller
SLS Graduate Symposium with Poster Presentation by Lauren
Great poster presentation by Lauren at the Annual SLS Graduate Student Symposium 2019.
under the umbrella of the GRP Science and Technology for Health an exciting new network with the goal to develop new E-health applications for physical activity, sleep and circadian rhythms has been founded including more than a dozen labs from all over campus. Looking forward to come together and see what is already here.