Dr Karuna Sampath
A*STAR Singapore liaison (Warwick Medical School)
Karuna Sampath is a Professor of Biomedicine, University of Warwick. Following her doctoral training at Indiana State University, USA with Gary Stuart, she did brief post-doctoral stints with Christopher Wright at Vanderbilt University, Nashville, USA (1995-1996), and Vladimir Korzh at the Institute of Molecular Agrobiology, Singapore (1997-1998). She was a visiting scientist at EMBL (host: Anne Ephrussi) in 1999, and started her independent programme in 2000 as a fellow at the Institute of Molecular Agrobiology, Singapore. She was a group leader at Temasek Life Sciences Laboratory, National University of Singapore from 2002-2013, and subsequently joined Warwick Medical School.
Research in the Sampath laboratory focusses on the fundamental mechanisms underlying embryonic differentiation and patterning. We are especially interested in RNA regulation of signalling pathways and germline development, primarily using zebrafish as a paradigm. A recent area of interest is how RNA elements are recognised by RNA binding protein complexes, and assemble into RNP granules in eggs and embryonic progenitors cells. We use a combination of computational and experimental approaches, including structural biology, epitranscriptomics, gene editing, live imaging and proteomics. Our work is funded by the BBSRC and the Leverhulme Trust.