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Biomedical Sciences

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Our research programme in Microbiology and Infection encompasses a spectrum of research that runs from the fundamental science of model organisms to translational research on human and animal pathogens. We exploit cutting-edge high-throughput approaches, including robotics, genomics, metagenomics, bioinformatics and rapid virulence assays to link basic science to clinical applications.

Biomedical Sciences News

Using unnatural sugars to target galectins

The GibsonGroup, as part of a large BBSRC/Innovate funded collaboration have published their latest results into using nanomaterials to probe glycan-binding events. In this collaborative work, a combined chemical and enzymatic synthetic route was exploited to generate glycans which could be attached to nanoparticles for glycan/lectin screening - a platform technology developed by the GibsonGroup. Using this approach, it was shown that selective addition of fluorine atoms allow selective binding of galectins which is not possible using natural disaccharides, and may offer a route for targeting therapies and diagnostics. https://doi.org/10.1039/D0SC05360K

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Senior Cancer Research UK Fellow Steve Royle tells us about his team's work looking at cell division and their research that could help develop cures for diseases including cancer.