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Seminar: Addressing the Threat of Multi-drug Resistant Gram Negative Infections

8 January 2014, 1.00pm-2.00pm, GLT2, Warwick Medical School Building, University of Warwick


Dr David Wareham, Blizard Institute of Cell and Molecular Science, School of Medicine and Dentistry, Queen Mary University of London


Multi-drug resistant (MDR) Gram-negative bacteria (GNB) represent a significant threat to modern healthcare systems. The emergence and spread of carbapenem resistant (CRO) strains of E. coli, K. pneumoniae (KPC / NDM), Acinetobacter (OXA) and Pseudomonas (IMP/ VIM) pose unique challenges for the effective management of hospital and community acquired infections. This talk will give an overview of the current epidemiology, detection, treatment and control of MDR Gram-negatives and the work undertaken in our group in an attempt to address the problem.



david warehamDavid Wareham qualified from the London Hospital Medical College in 1994 and trained in general medicine in and around London before specialist training in Medical Microbiology in North East Thames. He was awarded a Clinical Training Fellowship to study aspects of Pseudomonas aeruginosa pathogenicity at Queen Mary University London in 2002 and was appointed as Senior Clinical Lecturer in Microbiology in July 2005. He founded and now leads the Antimicrobial Research Group within the Centre for Immunology and Infectious Diseases at Barts and The London School of Medicine and Dentistry, whose research interests include the molecular epidemiology, mechanisms of resistance and pathogenicity of multi-drug resistant Gram-negative pathogens. David is also an Honorary Consultant Microbiologist at Barts Health NHS Trust, Newham University and Homerton NHS Trusts where he is responsible for aspects of intensive care microbiology and chairs the trust Antimicrobial Review Group.