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Delivery of Patient Care

Within Metabolic and Vascular Health, there is a continuum of academic and clinical interest that extends from bench to bedside and back. Several of its members conduct research on the way that care is delivered within the NHS, and how to improve outcomes in line with the necessity for medicine to be evidence-based, including the assessment of the effectiveness of medical treatments.

Some initiate or are otherwise involved in clinical trials through national and local clinical research networks (e.g. in Diabetes, Stroke). Others gain insight for their basic research from their day-to-day involvement in the delivery of clinical care. This makes for a modern, translational approach to the improvement of patient care, and the use of resources for the benefit of health care delivery.

Principal Investigators

Harpal Randeva


Dr Harpal Randeva Senior Lecturer (Clinical)

Research interests: Complex Endocrinological and Metabolic Disorders

Paul O

Dr Paul O'Hare
Director of Quality Assurance

Research interests: Prevention and treatment of diabetes in resource-poor settings


Dr Narendra Reddy
Clinical Lecturer

Research interests: Body-weight control in adult obesity



Ponnusamy Saravanan

Dr Ponnusamy Saravanan
Associate Clinical Professor

Research interests: Nutritional and clinical management of diabetes



Dr Daniel Zehnder
Senior Lecturer (Clinical)

Research interests: Biomarkers and treatment of metabolic cardiovascular disease; Antibody-incompatible renal transplantation

Recent Publications

  • Bellary, S., J. P. O'Hare, N. T. Raymond, S. Mughal, W. M. Hanif, A. Jones, S. Kumar and A. H. Barnett (2010). "Premature cardiovascular events and mortality in south Asians with type 2 diabetes in the United Kingdom Asian Diabetes Study - effect of ethnicity on risk." Curr Med Res Opin 26(8): 1873-1879.
  • D'Elia, L., G. Barba, F. P. Cappuccio and P. Strazzullo (2011). "Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies." J Am Coll Cardiol 57(10): 1210-1219.
  • Osei-Assibey, G., Y. Adi, I. Kyrou, S. Kumar and K. Matyka (2010). "Pharmacotherapy for overweight/obesity in ethnic minorities and white Caucasians: a systematic review and meta-analysis." Diabetes Obes Metab.
  • Rafnsson, S. B., P. Saravanan, R. S. Bhopal and C. S. Yajnik (2011). "Is a low blood level of vitamin B12 a cardiovascular and diabetes risk factor? A systematic review of cohort studies." Eur J Nutr 50(2): 97-106.
  • Sturt, J. (2011). "Higher consumption of sugar-sweetened beverages is associated with increased risk of developing type 2 diabetes or metabolic syndrome." Evid Based Nurs 14(2): 35.
  • Thadhani, R., E. Appelbaum, Y. Chang, Y. Pritchett, I. Bhan, R. Agarwal, C. Zoccali, C. Wanner, D. Lloyd-Jones, J. Cannata, T. Thompson, P. Audhya, D. Andress, W. Zhang, J. Ye, D. Packham, B. Singh, D. Zehnder, W. J. Manning, A. Pachika and S. D. Solomon (2011). "Vitamin D receptor activation and left ventricular hypertrophy in advanced kidney disease." Am J Nephrol 33(2): 139-149