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PRiDE Study

  • A pregnant mother has a 1 in 6 chance of developing gestational diabetes mellitus (GDM)
  • The risk of GDM is even higher in mothers of South Asian origin and other Ethnic Minority groups
  • GDM can affect any mother. Though older age, higher body mass index (BMI) and family history of diabetes are high risk factors for developing GDM, there are a significant number of cases which cannot be explained by these factors
  • Mothers who had GDM during their pregnancy are at 7 to 8 times higher risk of developing Type 2 Diabetes later on in their life
  • Birth weight of the babies born to mothers with GDM can be large and are also at risk of type 2 diabetes or obesity in childhood and adult life. Therefore GDM affects not only a mum but can have an impact on her future generations

More than 500 mothers in Coventry and Warwickshire alone are diagnosed to have GDM every year. To understand why the local population has such a high risk, the PRiDE study was designed and funded by the Medical Research Council (MRC), UK.

The PRiDE study is a collaborative effort by University of Warwick, University of Southampton and a premier Indian diabetes research institution. The study is sponsored by University of Warwick and George Eliot Hospital. It has the support of the Research Networks and Research & Development departments of the Primary and Secondary NHS Trusts involved in Coventry and Warwickshire.

The overall aim is to look at various risk factors for the development of GDM, particularly the role of certain nutrients such as Vitamin B12 and folate. In doing so, we hope to identify a unique cohort of mothers whom we will be closely following up throughout their pregnancies and also of their babies right though infancy and childhood.

With everyone of us playing a part in the PRiDE study, we can truly create a legacy which will influence and improve the health of women and children in our region for years to come!