Molecular Cell Biology
Mohan Balasubramanian (Medical School) l Synthetic Cell Biology: Using biophysics and chemistry to understand molecular mechanisms of actomyosin ring dependent eukaryotic cell division l see: Huang et all, eLife, 2016.
Andrew Blanks (Medical School) l Reproduction in mammals, parturition and preterm birth, drug discovery, computational biology of bioelectrical systems l see: Jolene et al, PLOS Computational Biology, 2016.
Andrew Bowman (Medical School) l Research utilises novel synthetic biology approaches and fluorescence microscopy to observe chromatin assembly in living cells l see: Bowman et al, Nucleic Acids Res., 2016.
Mark Christian (Medical School) l Understanding the processes that control energy metabolism in brown adipocytes and have the potential to be targeted for weight loss treatments l see: Barneda et al, eLife, 2015.
Robert Dallmann (Medical School) l Circadian clocks in health, disease and pharmacotherapy l see: DeBruyne JP et al, 2014.
Geraldine Hartshorne (Medical School) l Human oocyte formation, selection, maturation and ageing; pre-implantation embryo development l see: Patel et al, Biology Open, 2015.
Judith Klein-Seetharaman (Medical School) l Structure-dynamics-function of membrane receptors; life-style biomarker discovery; protein-protein and protein-lipid interactions; cardiolipin interactions with proteins. l see: Planas-Iglesias et al, Biophys. J., 2015.
Andrew McAinsh (Centre for Mechanochemical Cell Biology) l Origins of chromosome mis-segregation in human disease and development, live-cell imaging, in vitro reconstitution, genome editing, image analysis l see: Smith et al, eLife, 2016.
Jonathan Millar (Centre for Mechanochemical Cell Biology) l The Millar lab studies the mechanism and deregulation of cell cycle checkpoints using live cell imaging, image analysis, phospho-proteomics, bioinformatics and genome editing in yeast and human cells l see: Mora-Santos et al, Current Biology, 2016.
Masanori Mishima (Medical School) l Molecular mechanisms of animal cytokinesis l see: Lee et al, Nat. Comms 6:7290, 2015.
Giacomo de Piccoli (Medical School) l How the S phase checkpoint regulates the replication machinery l see: Garcia-Rodriguez LJ et al, Nucleic Acids Res., 2015.
Steve Royle (Centre for Mechanochemical Cell Biology) l Mitotic spindle stability in human cells; molecules and mechanics of clathrin-mediated endocytosis l see: Nixon et al, eLife 4:e07635, 2015.
Karuna Sampath (Medical School) l Molecular mechanisms that control development and differentiation in embryonic progenitors using live-imaging, proteomics, genome editing, quantitative approaches and zebrafish developmental genetics l see: Yin et al, eLife 5:e13879, 2016.
Anne Straube (Centre for Mechanochemical Cell Biology) l Mechanisms of microtubule organisation and dynamics regulation; microtubule functions in cell differentiation and migration l see: Mogessie et al, eLife, 2015.
Bee Tan (Medical School) l Mechanisms of embryo implantation.
Mark Achtman (Medical School) l Reconstruction of the evolutionary history of bacterial pathogens by combining ancient DNA analyses with population genetics of extant organisms l see: Zhou et al, PNAS, 2014.
Chrystala Constantinidou (Medical School) l Microbial pathogenesis through the study of secretion systems, motility and genomics analysis l see: Loman et al, JAMA, 2013.
Emma Denham (Medical School) l Understanding the role non-coding RNAs play in the lifestyles of Gram-positive bacteria, mainly focusing on the model organism Bacillus subtilis, but with a developing interest in Gram-Positive pathogens from the Streptococci group l see: Mars et al, PLOS Genetics, 2015.
Andrew Millard (Medical School) l Role of bacteriophages in the transfer of antibiotic resistance genes and the potential of bacteriophages as a therapeutic agent.
Meera Unnikrishnan (Medical School) l Understanding how clinically important bacterial pathogens colonise the host, invade and survive within host cells using a combination of whole genome-based and cellular methodologies l see: Dapa et al, J. Bacteriol., 2013.
Nick Waterfield (Medical School) l Understanding the molecular mechanisms employed by bacterial pathogens to achieve virulence in insect and human hosts, more specifically how certain insect pathogens have evolved to infect humans also. l see: Mulley et al, PLoS One, 2015.
A*STAR Research Institutes (Singapore)