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AirPROM (Airway Disease Predicting Outcomes through Patient Specific Computational Modelling)

dsc_6492.jpgThe EU-funded programme AirPROM aims to develop models of the airways to assess how air flows through the lungs and why this flow becomes obstructed in people with asthma and COPD. This will enable development and testing of new individually tailored therapies, through linking the characteristics of different airways to a particular treatment.

As part of this project, techniques are developed to study flows in human conducting airways to improve understanding of underlying mechanisms in asthma and COPD. For this, realistic patient-specific anatomical models of the conducting airways are created through additive layer manufacturing (ALM) of segmented in vivo lung CT scans, which allow the airflow in lungs to be studied to understand how lung-conditions affect the patients’ breathing.

Videos:

BBC Click, 23 May 2015: watch how additive manufacturing is developing, showing some of our recent airway models. http://www.bbc.co.uk/iplayer/episode/b05wdq7y/click-23052015 (WMG starting at ~21minutes)

upper airwayFurther reading:

www.airprom.eu

(PDF Document) Flow Measurements in Patient Specific Conducting Airways Models: Towards Tailoring Treatment of Asthma and COPD

 (PDF Document) Flow Measurements in Patient Specific Conducting Airways Models

(PDF Document) Additive Layer Manufacturing (3D Printing) of Physiologically Realistic Patient Specific Airway Models for Study of Flow Modifications in Asthma and COPD

For Optical Diagnostics used: http://www.eng.warwick.ac.uk/oel/; OEL

Nebuliser/spray diagnostic

airpromlogocoloursmaller.jpgEU-logo-low

This project has received funding from the European Union's Seventh Framework Programme for research, technological development and demonstration under grant agreement no 270194.

AirPROM: "Airway Disease PRedicting Outcomes through Patient Specific Computational Modelling"

Key Contact:

Dr Greg Gibbons
ALM Group Lead

Dr Brenda Timmerman
Senior Research Fellow Profile