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CH270 - Selective Organic Synthesis

  • Module code: CH270
  • Module name: Selective Organic Synthesis
  • Department: Chemistry
  • Credit: 15

Content and teaching | Assessment | Availability

Module content and teaching

Principal aims

This module builds on first year organic chemistry using your understanding of functional group reactivity to explore substituent effects on the electrophilic and nucleophilic substitution of aromatics. The introduction of heteroatoms into these systems provides a wealth of new chemistry and reactivity to be explored. Then transition metal catalysis for C-C bond forming will be examined as a counterpoint to earlier synthetic approaches. The scope of the course then broadens to provide a range of synthetic chemistry to undertake many key functional group transformations. Reactions to form carbon-carbon single, double and triple bonds will be covered as well as their related oxidative cleavage. Oxidative and reductive reactions of carbon-heteroatom bonds will offer a complimentary picture of functional group manipulation. Many examples of regio- and stereoselectivity in these transformations will be highlighted. Finally, all this will be combined in the form of retrosynthetic analysis as a tool to develop your own strategies in organic synthesis.

Principal learning outcomes

By the end of the module the student should be able to: Differentiate the ring substituents on benzene into activating and deactivating, and ortho/para or meta directing. Understand the role hetero atoms play in the chemistry of heteroaromatic systems. Describe the synthesis and chemistry of aliphatic heterocyclic compounds. Understand how & when to use organopalladium chemistry in biaryl and alkyne aryl synthesis Develop a solid grounding of the mechanisms of a wide range of organic chemical reactions and transformations Understand and apply a wide range of important chemical transformations of use in modern organic synthesis. As well as revision, further application of important organic reactions seen in year 1 and the exposure to a significant number of new reactions Develop solutions to problems in organic chemistry using retrosynthetic analysis. Learn to use software packages to search the chemical literature using key words, structural and partial structural queries to find reaction conditions to guide retrosynthetic analysis of target organic molecules and source spectral data and physical properties

Timetabled teaching activities

30 lectures 2 workshops 4 tutorials 2 revision sessions

Departmental link

go.warwick.ac.uk/CH270

Module assessment

Assessment group Assessment name Percentage
15 CATS (Module code: CH270-15)
D (Assessed/examined work) Workshop reports 20%
  1.5 hour examination (Summer) 80%

Module availability

This module is available on the following courses:

Core
  • Undergraduate Chemistry 3 Year Variants (F100) - Year 2
  • Undergraduate Chemistry (with Intercalated Year) Variants (F101) - Year 2
  • Undergraduate Master of Chemistry Variants (F105) - Year 2
  • Undergraduate Master of Chemistry (with Intercalated Year) (F107) - Year 2
  • Undergraduate Master of Chemistry (with International Placement) (F109) - Year 2
  • Undergraduate Master of Chemistry Variants (F109) - Year 2
  • Undergraduate Master of Chemistry (with Industrial Placement) (F110) - Year 2
  • Undergraduate Master of Chemistry Variants (F110) - Year 2
  • Undergraduate Master of Chemistry (with International Placement) (F111) - Year 2
  • Undergraduate Master of Chemistry (with Industrial Placement) (F112) - Year 2
  • Undergraduate Chemistry 3 Year Variants (F121) - Year 2
  • Undergraduate Chemistry (with Intercalated Year) Variants (F122) - Year 2
  • Undergraduate Master of Chemistry Variants (F125) - Year 2
  • Undergraduate Master of Chemistry with Medicinal Chemistry(with Intercalated Year) (F127) - Year 2
  • Undergraduate Chemistry and Business Studies (FN11) - Year 2
Optional Core

N/A

Optional

N/A