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BEGIN:VEVENT
DTSTAMP:20260406T233726Z
DTSTART;VALUE=DATE-TIME:20170531T130000
DTEND;VALUE=DATE-TIME:20170531T140000
SUMMARY:Complexity Forum: Iain Johnston (University of Birmingham)
TZID:Europe/London
UID:20170531-094d4345535bd8de0153a2de6e86205d@warwick.ac.uk
CREATED:20160322T124517Z
DESCRIPTION:Evolution of cell-to-cell variability in stochastic\, control
 led\, heteroplasmic mtDNA populations Populations of mtDNA molecules exi
 st in our cells\, under the control of our nuclei\, and replicating and 
 degrading independently of the cell cycle. These evolving cellular popul
 ations encode energetically vital cellular machinery and have strikingly
  nonlinear effects on cell physiology: if the proportion of mutant molec
 ules comes to pass a threshold value\, deadly and incurable diseases bec
 ome manifest. It's therefore vital to understand not just the mean behav
 iour of mtDNA populations but also their cell-to-cell variance. I'll tal
 k about our work using stochastic modelling to describe and predict biom
 edically important properties of these evolving cellular populations.
LOCATION:D1.07 Complexity Science
CATEGORIES:Seminar Room D1.07,forum
LAST-MODIFIED:20170530T150350Z
ORGANIZER;CN=Heather Robson:
END:VEVENT
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