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BEGIN:VEVENT
DTSTAMP:20260407T212756Z
DTSTART;VALUE=DATE-TIME:20160428T140000
DTEND;VALUE=DATE-TIME:20160428T150000
SUMMARY:The Regulation of Brain State by Sensory Stimuli
TZID:Europe/London
UID:20160428-094d434553e1cda701541a0782a40334@warwick.ac.uk
CREATED:20160415T130620Z
DESCRIPTION:Time: 2.00pm Location: GLT3 Speaker: Dr Suresh Jesuthasan\, L
 KC School of Medicine\, Singapore. Institute of Molecular and Cell Biolo
 gy\, Singapore. Abstract Animals face a constantly changing environment\
 , but are usually able to react to stimuli in a manner that is appropria
 te for a given situation. Failure to do so compromises survival\; in hum
 ans\, inability to react appropriately is a hallmark of psychiatric dise
 ase. We use the zebrafish to investigate how the brain achieves a high d
 egree of flexibility. A central assumption is that the functional networ
 k mediating behavior is selected by the release of neuromodulators that 
 are appropriate for that context. The question thus boils down to how mo
 dulators are precisely regulated. We propose that the evolutionarily con
 served habenula has an important role\, due to its innervation by multip
 le sensory and reward systems\, and its ability to regulate a broad rang
 e of neuromodulators. Current experiments are aimed at understanding how
  the habenula is able to process a large amount of information to give a
  coherent output. In this regard\, the zebrafish has distinct advantages
  compared to other vertebrate model systems – in addition to the amenabi
 lity of the system to genetic manipulation\, the habenula is located in 
 a dorsal position and is thus accessible to optical recording and manipu
 lation. It is anticipated that the zebrafish will provide unique insight
 s into how the habenula functions\, and thus shed light on mental and ne
 urological disease.
LOCATION:GLT3\, Warwick Medical School Building
URL:http://www2.warwick.ac.uk/fac/med/research/biomedical/seminars
ATTACH:http://www2.warwick.ac.uk/fac/med/research/biomedical/seminars
CATEGORIES:DivisionalSeminars
LAST-MODIFIED:20160415T130653Z
ORGANIZER;CN=Becks Andrew:
END:VEVENT
END:VCALENDAR