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BEGIN:VEVENT
DTSTAMP:20260405T223507Z
DTSTART;VALUE=DATE-TIME:20210427T120000
DTEND;VALUE=DATE-TIME:20210427T130000
SUMMARY:SLS/WMS Micro Webinar: RNA Structure in Influenza and Coronavirus
 es: A Comparison\, Dr David Bauer\, Francis Crick Institute
TZID:Europe/London
UID:20210427-8a1785d8756ec87401758d4ffc913c7d@warwick.ac.uk
CREATED:20210427T085604Z
DESCRIPTION:RNA viruses cause a wide range of diseases in humans\, from t
 he common cold to more severe illnesses such as gastroenteritis\, influe
 nza\, Ebola virus disease\, measles and COVID-19. The use of RNA (instea
 d of DNA) by these viruses gives them unique properties since\, unlike D
 NA\, RNA can adopt specific shapes that allow the genome itself to carry
  out structural and enzymatic functions directly\, even though it is not
  a protein or an enzyme in a conventional sense. All RNA viruses exploit
  this unique property of RNA in one way or another. This feature is expl
 oited by all RNA viruses in one way or another. Coronaviruses\, for exam
 ple\, use RNA structures to regulate their own genome replication\, as w
 ell as to interact with host ribosomes. Influenza viruses use RNA struct
 ure to control splicing of viral genes and to drive reassortment of thei
 r eight genomic segments — the process that gives rise to new pandemic s
 trains. Much of the details about how RNA structures act (and interact) 
 during infection remains unknown. I will discuss our recent work on usin
 g high-throughput chemical probing coupled with high-throughput sequenci
 ng in order to map RNA structures in influenza A virus and in SARS-CoV-2
 .
LOCATION:via Teams
CATEGORIES:BiomedicalSciences,DivisionalSeminars,Joint WMS/SLS Micro
LAST-MODIFIED:20210427T085604Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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