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BEGIN:VEVENT
DTSTAMP:20260412T105020Z
DTSTART;VALUE=DATE-TIME:20251112T131500
DTEND;VALUE=DATE-TIME:20251112T141500
SUMMARY:BMS Seminar: Gene Processing using DonorGuide\, GeneWeld and Mito
 FUSX Base Editors\, Professor Steve Ekker\, Department of Pediatrics\, D
 ell Medical School\, University of Texas Austin
TZID:Europe/London
UID:20251112-8ac672c699e717d30199e78bb94f096a@warwick.ac.uk
CREATED:20251020T093908Z
DESCRIPTION:Abstract: The Ekker Precision Gene Editing Laboratory develop
 ed morpholinos\, gene-breaking and other transposon tools\, and the firs
 t HDR editing in zebrafish. Recent gene editing advances include precisi
 on targeted large knockins using GeneWeld\, smaller knockins using Donor
 Guide\, and new programmable edits in the mitochondrial genome. This pre
 sentation will include technical and application updates for each approa
 ch\, enabling the massive parallel assessment of AI-based CAR-T therapie
 s\, and the establishment of the first unconstrained mitochondrial TALE 
 base editors. Recent advances in AI- prediction tools enable rational st
 ructure-based design of next generation gene editing tools including Zip
 pered Donor Guide and mitoFUSX TALE base editors.
LOCATION:IBRB Lecture Theatre
CATEGORIES:BiomedicalSciences,Directorate Seminars
LAST-MODIFIED:20251020T093908Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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