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BEGIN:VEVENT
DTSTAMP:20260430T215047Z
DTSTART;VALUE=DATE-TIME:20260326T143000
DTEND;VALUE=DATE-TIME:20260326T153000
SUMMARY:BMS Seminar: Understanding the in vivo dynamics of distinct muscl
 e stem cells systems during growth and regeneration and their different 
 niches across the vertebrate phylogeny\, Professor Peter Currie\, Monash
  University
TZID:Europe/London
UID:20260326-8ac672c69c8a6b40019c99d621053375@warwick.ac.uk
CREATED:20260227T105332Z
DESCRIPTION:Abstract: While the function of adult tissue-resident stem ce
 lls during regeneration and disease have received much attention\, the m
 echanistic basis of stem cell driven organ growth remains relatively poo
 rly defined. Consequently\, our understanding of processes that drive or
 gan development remains piecemeal. Understanding stem cell dynamics with
 in the organ systems that deploy them to generate growth is critical for
  the success of ongoing efforts to generate complex functioning organs f
 rom organoid rudiments in vitro. Thus\, we have sought to understand the
  stem cell processes that regulate and drive myotomal growth from the te
 mplate of the embryonic myotome using zebrafish as our main model system
 . Here we compare and contrast modes of myotomal growth and muscle regen
 eration and their molecular regulation in distinct niches across the phy
 logeny\, in attempt to generate a fuller understanding of the way muscle
  stem cells act within different vertebrate clades. Biography: Professor
  Peter Currie is a world-renowned developmental evolutionary and stem ce
 ll biologist who studies the genetic basis of skeletal muscle stem cell 
 action during development\, evolution\, regeneration and disease. His ke
 y discoveries utilise several models\, chiefly the zebrafish\, to define
  the genetic and evolutionary basis for muscle formation and growth thro
 ughout vertebrate phylogeny. Prof Currie has played a key role globally 
 in developing zebrafish as a disease model for human muscle disease and 
 regeneration biology. He has also been instrumental in establishing shar
 k embryology as a modern evolutionary paradigm to understand the evoluti
 onary origins of the vertebrate body plan. In 2016\, Professor Peter Cur
 rie was appointed Director of Research of the Australian Regenerative Me
 dicine Institute at Monash University in Melbourne\, Australia. He is a 
 recipient of a European Molecular Biology Organization Young Investigato
 rs Award and a Wellcome Trust International Research Fellowship and curr
 ently is a Principal Research Fellow with the National Health and Medica
 l Research Council in Australia and an elected Fellow of the Australian 
 Academy of Science.
LOCATION:GLT3\, Medical School Building
CATEGORIES:BiomedicalSciences,Directorate Seminars
LAST-MODIFIED:20260227T105332Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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