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BEGIN:VEVENT
DTSTAMP:20260809T043926Z
DTSTART;VALUE=DATE-TIME:20240306T130000
DTEND;VALUE=DATE-TIME:20240306T140000
SUMMARY:BMS Seminar: Curiouser and curiouser: regulating the remarkable i
 ntracellular dynamics of killer T cells\, Professor Gillian Griffiths\, 
 Cambridge Institute for Medical Research
TZID:Europe/London
UID:20240306-8a1785d78defef9d018df576d67449a3@warwick.ac.uk
CREATED:20240229T152448Z
DESCRIPTION:Abstract: Killer cells of the immune system provide a vital d
 efence against pathogens and cancer. There is increasing interest in und
 erstanding how these cells work as recent advances in immunotherapies ha
 ve successfully harnessed the killing potential of these cells to combat
  cancers. How best to optimise these treatments and regulate killing is 
 the subject of intense research. However\, most research to date has foc
 used on modifying the receptors that recognise targets at the cell surfa
 ce. In this seminar I will describe what happens underneath the surface 
 of these cells when they encounter their targets and the multiple mechan
 isms that regulate killer cell function by mechanisms that are both unus
 ual and fascinating\, linking rapid membrane changes to changes in trans
 cription\, translation and intracellular polarity that are all required 
 for optimal killing. Short biography: Professor Gillian Griffiths obtain
 ed her PhD at the MRC Laboratory of Molecular Biology with Cesar Milstei
 n. After a post-doctoral fellowship at Stanford University\, she started
  her own research laboratory at the Basel Institute for Immunology in Sw
 itzerland in 1990. She subsequently held posts at University College Lon
 don\, the Dunn School of Pathology\, Oxford (1997-2007) before moving to
  the Cambridge Institute for Medical Research where she was Director 210
 2-2017. She was elected as a Fellow of the Academy of Medical Sciences (
 2005)\; EMBO (2006)\, and the Royal Society (2013). She was awarded the 
 Royal Society Buchanan medal (2019) in recognition of her ground-breakin
 g research establishing the fundamental cell biological mechanisms that 
 drive CTL killing\, laying the foundations for the development of target
 ed cancer immunotherapy
LOCATION:A151\, Medical School Building
CATEGORIES:BiomedicalSciences,DivisionalSeminars
LAST-MODIFIED:20240229T152448Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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