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BEGIN:VEVENT
DTSTAMP:20260720T010914Z
DTSTART;VALUE=DATE-TIME:20250226T131500
DTEND;VALUE=DATE-TIME:20250226T141500
SUMMARY:BMS Seminar: Preparing for the Next Generation: Understanding Epi
 genetic Remodelling in the Human Germline by Dr Wolfram Gruhn\; Assembly
  of eukaryotic flagella – lessons from the small and mighty trypanosome\
 , Dr Samuel Dean
TZID:Europe/London
UID:20250226-8ac672c493d938df0193da57b8770edd@warwick.ac.uk
CREATED:20250210T081937Z
DESCRIPTION:Preparing for the Next Generation: Understanding Epigenetic R
 emodelling in the Human Germline Dr Wolfram Gruhn\, Assistant Professor\
 , Biomedical Sciences Directorate\, WMS Abstract: In most multicellular 
 species\, the germline forms the foundation of the life cycle\, serving 
 as an enduring link between generations. In humans\, the process of form
 ing sperm and eggs is initiated in the early embryo and spans more than 
 a decade. During this time\, developing germ cells undergo profound epig
 enetic changes and mitochondrial selection\, processes that promote cell
 ular "rejuvenation" and establish the foundation for normal development 
 in the next generation. Disruptions in these processes can result in inf
 ertility\, cancer\, or abnormal offspring development. Here\, I will dis
 cuss our efforts to decipher epigenetic remodelling in human primordial 
 germ cells and our strategies to recapitulate this process using embryon
 ic stem cell-derived systems. Assembly of eukaryotic flagella – lessons 
 from the small and mighty trypanosome Dr Samuel Dean\, Associate Profess
 or\, Biomedical Sciences Directorate\, WMS Abstract: Our research invest
 igates the molecular mechanisms of eukaryotic flagella assembly using Af
 rican trypanosomes as a model organism. These pathogenic protozoa rely o
 n their flagella for virulence and transmission. We specifically focus o
 n characterising assembly and nucleation factors located in a key subdom
 ain at the flagellar base\, aiming to better understand the construction
  and regulation of these essential organelles.
LOCATION:IBRB Lecture Theatre
CATEGORIES:BiomedicalSciences,Directorate Seminars
LAST-MODIFIED:20250210T081937Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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