Aims of the Centre:

Interdisciplinary, cross-scale mechanistic enzymology of bacterial cell wall research in silico, in vitro, and in vivo, with a focus upon translation to help tackle antimicrobial resistance (AMR).

Retain expertise within Warwick as a centre from which to train the next generation of researchers, nationally and internationally.

Develop closer links with industry and joint research with other centres of excellence in antimicrobial research, and AMR science policy, to advance translational research.

Establish the Centre as internationally recognized for AMR focused mechanistic enzymology based on the excellence of its research, training, and impact.

Discover more about the centre and about our approaches to research:

• Collaborative research
• Capabilities
• Working with industry
• Global research

Launch of the Centre

On Thursday 20 October 2022, a launch event was held for the Sir Howard Dalton Centre for Translational Mechanistic Enzymology at the University of Warwick. The event was attended by Dr David Stirling, his former classmates, Sir Howard’s family and former colleagues and members of the antimicrobial resistance research community. Press release

Benefactors

The University of Warwick will be pleased to discuss a range of recognition opportunities to celebrate donations to build upon antimicrobial research at Warwick, and to train the next generation of researchers. If you would like to find out more information or discuss these opportunities further please visit our contact page.

News

A “zinc” in the armour: could metal help combat common superbug?

A new study has shown that zinc plays a key role in a hospital superbug, that doctors struggle to treat due to its resistance to antibiotics. Press Release

New study into Tuberculosis membrane molecules will aid drug delivery

TB rivals covid-19 as the biggest infectious disease killer of humans, claiming millions of lives each year. Now, ground-breaking research from the Universities of Warwick and Toulouse has identified a new method to help tackle this global issue. Press Release

Publications

Fri 15 Sep '23

Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex

Mon 07 Aug '23

PLSCR1 is a cell-autonomous defense factor against SARS-CoV-2 infection

Wed 19 Jul '23

Cyclic di-AMP traps proton-coupled K+ transporters of the KUP family in an inward-occluded conformation