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Allergic Sensitisation sub-study


To estimate the rate of allergic sensitisation to sugammadex and the future risk of anaphylaxis under anaesthesia.


In SINFONIA trial hospitals with well-established regional allergy services, we will carry out, with participant consent, an observational sub-study to investigate the incidence of allergic sensitisation to sugammadex. This will comprise a baseline blood sample on the day or surgery, with an outpatient clinic visit between 6 weeks and 6 months post-operatively to undertake further blood and skin testing for allergic sensitisation.