Datamining Medieval Medical Texts for Modern Medicines
Dr Erin Connelly's Fellowship is an international, interdisciplinary project exploring questions of ethnopharmacology and the antimicrobial efficacy of ingredients from historical and traditional medical sources.
Medieval manuscripts contain numerous remedies for the treatment of microbial infections, and these often involve complex preparations of several ingredients.
Analysing historical recipes in extant medical books
The research involves quantitative analyses of historical recipes in surviving medical books, and empirical tests of the antimicrobial activity of remedies inspired by historical combinations. Using network analysis tools to analyse medieval medical texts is a new way to identify potentially effective ingredient combinations. This is a novel route to developing new antimicrobial therapeutics in a time of increasing antimicrobial resistance.
Lylye of Medicynes, Oxford, Bodleian Library, MS Ashmole 1505.
'Urine Wheel' from a medieval doctor's belt book (Free Library of Philadelphia, The Rosenbach, MS 1004 29).
Prior to her Fellowship, Dr Connelly worked on a number of collaborative, interdisciplinary projects. These included digitisation and creation of metadata for around 400 medieval manuscripts (Bibliotheca Philadelphiensis), analysis of stains in medieval manuscripts using multi-spectral imaging (Labeculae vivae), Datamining the Lylye of Medicynes, and the APEX supported project Nettles and Networks.
- Connelly, Erin; del Genio, Charo I.; Harrison, Freya, ‘Datamining a medieval medical text reveals patterns in ingredient choice that reflect biological activity against the causative agents of specified infections,’ mBio (2020)
- Harrison, Freya and Connelly, Erin, ‘Could Medieval Medicine Help the Fight Against Antimicrobial Resistance?’ in Chris Jones; Conor Kostick; and Klaus Oschema (eds), Making the Medieval Relevant (2019)
- Connelly, Erin, ‘A Case Study of Plantago in the Treatment of Infected Wounds in the Middle English Translation of Bernard of Gordon’s Lilium medicinae,’ in Erin Connelly; Stefanie Künzel (eds), New Approaches to Disease, Disability, and Medicine in Medieval Europe, Studies in Early Medicine (2018)
- Connelly, Erin, ‘My Written Books of Surgery in the Englishe Tonge: The London Company of Barber-Surgeons and the Lylye of Medicynes,’ Manuscript Studies, A Journal of the Schoenberg Institute for Manuscript Studies 2.2 (2017)
- Lecture for Topics in Preservation Series, Library of Congress
- NPR, radio interview