Cryo Transmission Electronic Microscopy (Cryo-TEM)
Cryo Transmission Electron Microscopy is a microscopy technique, using the Tranmission Electron Microscopy to observe specimens under cryo temperature conditions.
How does it work?
Specimens are flash frozen to produce a thin film of vitreous ice allowing a sample to be viewed under the electron microscope without the need for fixation, drying or staining.
The sample is viewed in a near native state without the distortions introduced by traditional EM methods.
Applications
Biological molecules; virology; nanotechnology; micelles; vesicles; emulsions.
Sample Handling Requirements:
Samples must be in aqueous suspension and contain particles less than 500nm thick.
Complementary Techniques
SEM, Standard TEM, Tomography.
Warwick Expertise
JEOL 2200 TEM, JEOL 2011 LaB6 TEM both cryo-capable with state of the art Gatan digital imaging.
Contact
Dr Ian Hancox, 024 76 150380 email i dot hancox at warwick dot ac dot uk.
Typical results format, and sample:
Status |
Availability |
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Warwick collect/analyse data |
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Warwick collect data |
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Available to user with expertise/ contribution |
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Spare capacity for collaborative research |
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