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Cryo Transmission Electronic Microscopy (Cryo-TEM)

Cryo Transmission Electron Microscopy is a microscopy technique, using the Tranmission Electron Microscopy to observe specimens under cryo temperature conditions.

How does it work?

Specimens are flash frozen to produce a thin film of vitreous ice allowing a sample to be viewed under the electron microscope without the need for fixation, drying or staining.

The sample is viewed in a near native state without the distortions introduced by traditional EM methods.

Applications

Biological molecules; virology; nanotechnology; micelles; vesicles; emulsions.

Sample Handling Requirements:

Samples must be in aqueous suspension and contain particles less than 500nm thick.

Complementary Techniques

SEM, Standard TEM, Tomography.

Warwick Expertise

JEOL 2200 TEM, JEOL 2011 LaB6 TEM both cryo-capable with state of the art Gatan digital imaging.

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Contact:

Claire Gerard: / 07385 145064