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Ion Mobility Mass Spectrometry (IMS)

Ion Mobility Spectrometry (IMS) is an analytical technique used to separate and identify ionized molecules in the gas phase based on their ion mobility in a carrier buffer gas.

How does it work?

Though heavily employed for military or security purposes, such as detecting drugs and explosives, the technique also has many laboratory analytical applications, recently being coupled with mass spectrometry and high performance liquid chromatography.

Applications:

Rapid (ms) separation of molecules based on shape, mass and charge. Protein structural studies, additional dimension in proteomics, ambient ionisation approaches, small molecule isomer separation.

Sample Handling Requirements:

Nanograms, or less, of material.

Complementary Techniques:

Circular Dichroism, XRD

Warwick Capability:

Waters Synapt G1, Waters Synapt G2

ion_mobility_equipment.jpg

Contact:

Claire Gerard: / 07385 145064