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Ion Mobility Mass Spectrometry (IMS)

Ion Mobility Spectrometry (IMS) is an analytical technique used to separate and identify ionized molecules in the gas phase based on their ion mobility in a carrier buffer gas.

cogsHow does it work?

Though heavily employed for military or security purposes, such as detecting drugs and explosives, the technique also has many laboratory analytical applications, recently being coupled with mass spectrometry and high performance liquid chromatography.


Rapid (ms) separation of molecules based on shape, mass and charge. Protein structural studies, additional dimension in proteomics, ambient ionisation approaches, small molecule isomer separation.

Sample Handling Requirements:

Nanograms, or less, of material.

Complementary Techniques:

Circular Dichroism, XRD

Warwick Capability:

Waters Synapt G1, Waters Synapt G2


Claire Gerard: c dot gerard at warwick dot ac dot uk / 07385 145064

IMS equipment

Typical results format, and sample:

IMS spectrum

green_tick.gif Warwick collect/analyse data
green_tick.gif Warwick collect data
 green_tick.gif Available to user with expertise/ contribution
 green_tick.gif Spare capacity for collaborative research