ePortfolio of Hattie Mintz (Harriet P Mintz)
Dr Hattie Mintz
Research
Completed PhD student at Warwick Medical School (October 2015-2019, submitted thesis 2019, viva January 2020 and passed) in the division of Health Sciences. Researching into the feasibility of using routinely collected healthcare data to identify randomised controlled trial outcomes in Oncology.
Research includes, identifying outcomes, such as, progressive disease events in prostate cancer, using routine clinical data alongside data from Professor Nick James' clinical trial STAMPEDE (Systemic Therapy in Advancing or Metastatic Prostate cancer: Evaluation of Drug Efficacy). STAMPEDE is the largest interventional prostate cancer clinical trial in the world. Also, researching into outcomes in bladder cancer for the new HTA funded clinical trial, BladderPath.
Main interests include identifying outcomes in metastatic or high-risk prostate cancer and bladder cancer. Working between Warwick Medical School and an honorary contract with the Queen Elizabeth Hospital Birmingham and the Medical Research Council Clinical Trials Unit London (MRC CTU).
Supervisors
Supervisors:
Professor Nicholas D. James (Honorary Professor or Clinical Oncology, Institute of Cancer and Genomic Sciences, University of Birmingham and Consultant in Clinical Oncology. Chief Investigator of STAMPEDE)
Dr Helen Parsons (Senior Research Fellow, Warwick Medical School)
Undergraduate study
BSc in Biomedical Science (Hons), First class from the University of Warwick
Postgraduate study
Enrolled onto the MScR in Health Sciences but upgraded to PhD April 2016
Submitted thesis September 2019, viva January 2020, now passed
Funding
Studentship awarded by Warwick Medical School
Presentations
- The Institute of Cancer Research, London; February 2020; Scheduled for London, due to COVID-20 the seminar was done virtually
- International Clinical Trials and Methodology Conference (ICTMC); October 2019; Brighton (oral)
- Postgraduate research induction; 4th October 2019; Warwick Medical School (oral)
- European Society of Medical Oncology (ESMO); September 2019; Barcelona (poster)
- Seminar series; 1st July 2019; Medical Research Council Clinical Trials Unit at UCL (MRC CTU at UCL) (oral)
- Trials Using Cohorts and Routine Health Data: International Symposium on their Efficiency and Analyses; 15th May 2019; London (poster)
- British Association of Urological Surgeons (BAUS) (co-author); 2019 (poster); Glasgow
- European Association of Urology (EAU) (co-author); 2019 (poster); Barcelona
- Midlands prostate cancer support group; 2018 (oral); Shakespeare hospice, Stratford-Upon-Avon
- Midlands Urology Club (MUC) annual meeting; September 2018; Awarded 3rd place; Hotel Ibis, Birmingham (oral)
- Warwick Medical School symposium; 2017 (poster), 2018 (oral); University of Warwick, Warwick Medical School
- Annual bladder cancer audit meeting (co-author); 2018; Queen Elizabeth Hospital Birmingham (oral)
- Midlands Academy of Medical Sciences Research Festival; 31st March 2017; University of Warwick
- American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancer Symposium; 16-18th February 2017; Rosen Shingle Creek, Florida, Orlando, USA - Poster can be viewed here
- West Midlands Informatics Network (WIN) Conference; 24th January 2017; University of Warwick - Slides can be viewed here
- Research poster showcase; 2016; University of Warwick (poster)
Publications
- Amandeep Dosanjh, Philip Harvey, Simon Baldwin, Harriet Mintz, Felicity Evison, Suzy Gallier, Nigel Trudgill, Nicholas D. James, Prasanna Sooriakumaran, Prashant Patel. High Intensity Focussed ultrasound (HIFU) for the Treatment of Prostate Cancer: A National Cohort Study Focussing on Development of Stricture and Fistulae. European Urology Focus. 2019. (accepted for publication)
- Harriet P. Mintz, Claire Amos, Rachael Brannan, Christopher Brawley, Joanna Calvert, Melissa R. Gannon, Luke Hounsome, Fiona C. Ingleby, Sean McPhail, Mahesh KB Parmar, Prashant Patel, Helen Parsons, Mary Rauchenberger, Matthew R. Sydes, Haiyan Wu, Nicholas D. James, the STAMPEDE trial group. Retrospective evaluation of neutropenic admission events in metastatic or high-risk hormone-sensitive prostate cancer (HSPC) patients having docetaxel chemotherapy upfront or for castrate-resistant prostate cancer (CRPC) in STAMPEDE. Annals of Oncology. 2019.
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Harriet P. Mintz, Amandeep Dosanjh, Ana Hughes, Alicia Jakeman, Nicholas D. James, Helen M. Parsons, Ann M. Pope, the BladderPath trial management group, Prashant Patel. Development and validation of a follow-up methodology for a randomised controlled trial, utilising routine clinical data as an alternative to traditional designs: a pilot study to assess the feasibility of use for the BladderPath trial. Pilot and Feasibility Studies. 2019. (pending review)
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Harriet P. Mintz, Claire Amos, Rachael Brannan, Christopher Brawley, Joanna Calvert, Amandeep Dosanjh, Melissa R. Gannon, Luke Hounsome, Ana Hughes, Fiona C. Ingleby, Alicia Jakeman, Sean McPhail, Mahesh KB Parmar, Prashant Patel, Helen Parsons, Ann M. Pope, Mary Rauchenberger, Matthew R. Sydes, Haiyan Wu, Nicholas D. James, the STAMPEDE trial group and the BladderPath trial group. The feasibility of using routinely collected data to inform outcomes in randomised controlled trials (RCT) in oncology. Trials journal. 2019. (pending publication of the abstract)
- A.Dosanjh, H.P.Mintz; J.L.Mytton; S.Gallier; N.D.James; P.Patel. Do urologists take the better slice of cake in muscle-invasive bladder cancer (MIBC)?. European urology. 2019.
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Amandeep Dosanjh, Philip Harvey, Simon Baldwin, Harriet Mintz, Felicity Evison, Nigel Trudgill, Nicholas James, Prasanna Sooriakumaran, Prashant Patel. High intensity focused ultrasound (HIFU) for prostate cancer: a national cohort study focusing on long term stricture and fistula. Journal of Clinical Urology. 2019.
- Harriet P. Mintz, Felicity Evison, Helen M. Parsons, Matthew R. Sydes, Melissa R. Spears, Prashant Patel, the STAMPEDE trial group, Nicholas D. James. National, centralised hospital datasets can inform clinical trial outcomes in prostate cancer: a pilot study in the STAMPEDE trial. Journal of Clinical Oncology. 2017. Poster can be viewed here
Member
American Society of Clinical Oncology (ASCO) : 2016 - present
European Association of Urology (EAU): 2018 - present
European Society for Medical Oncology (ESMO): 2019 - present
West Midlands Informatics Network (WIN)
Contracts
Honorary contract University Hospitals Birmingham, Queen Elizabeth Hospital Birmingham
Research fellow at the Medical Research Council Clinical Trials Unit at UCL (MRC CTU at UCL)
Research fellow at the University of Birmingham, College of Medical and Dental Sciences, Institute of Cancer and Genomic Sciences
