Rebecca Notman Group
Rebecca Notman Group
We use molecular dynamics computer simulations to investigate biomolecular systems with a range of important applications in biomedicine, pharmaceutical science and materials science. A particular focus of our current research is on understanding the barrier and elastic properties of skin and strategies to enhance drug delivery through skin (transdermal drug delivery).
Recent Publications
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Impact of oxetane incorporation on the structure and stability of alpha-helical peptides, ES Jayawant, JD Beadle, I Wilkening, P Raubo, M Shipman, R Notman and AM Dixon, Phys. Chem. Chem. Phys., 2020, 22, 25075-25083 (abstract).
- Comparison of umbrella sampling and steered molecular dynamics methods for computing free energy profiles of aromatic substrates through phospholipid bilayers, SY Noh, R Notman, J. Chem. Phys. 2020, 153, 034115 (abstract).
- The aggregation of striped nanoparticles in mixed phospholipid bilayers, SY Noh, A Nash, R Notman, Nanoscale 2020, 12, 4868-4881 (abstract).
- Macrocyclisation of small peptides enabled by oxetane incorporation, S Roesner, GJ Saunders, I Wilkening, E Jayawant, JV Geden, P Kerby, AM Dixon, R Notman and M Shipman, Chem. Sci. 2019, 10, 2465-2472 (abstract).
News
- Welcome to Sam and Theo who are joining us to carry out their MChem projects this year. (Oct 2022)
- Welcome to Callum Ward who is joining us to undertake a PhD on modelling the dermal absorption of agrochemicals. (Oct 2022)