Rebecca Notman Group
We use molecular dynamics computer simulations to investigate biomolecular systems with a range of important applications in biomedicine, pharmaceutical science and materials science. A particular focus of our current research is on understanding the barrier and elastic properties of skin and strategies to enhance drug delivery through skin (transdermal drug delivery).
Impact of oxetane incorporation on the structure and stability of alpha-helical peptides, ES Jayawant, JD Beadle, I Wilkening, P Raubo, M Shipman, R Notman and AM Dixon, Phys. Chem. Chem. Phys., 2020, 22, 25075-25083 (abstract).
- Comparison of umbrella sampling and steered molecular dynamics methods for computing free energy profiles of aromatic substrates through phospholipid bilayers, SY Noh, R Notman, J. Chem. Phys. 2020, 153, 034115 (abstract).
- The aggregation of striped nanoparticles in mixed phospholipid bilayers, SY Noh, A Nash, R Notman, Nanoscale 2020, 12, 4868-4881 (abstract).
- Macrocyclisation of small peptides enabled by oxetane incorporation, S Roesner, GJ Saunders, I Wilkening, E Jayawant, JV Geden, P Kerby, AM Dixon, R Notman and M Shipman, Chem. Sci. 2019, 10, 2465-2472 (abstract).