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Research Projects

Projects conducted within the framework of the current contract with NICE / NIHR

Warwick Evidence receives funding from the NIHR HTA Programme and the National Institute for Health and Care Excellence (NICE). The total allocated funding for the current contract running from April 2016 until April 2021 is £4,500,000. In the framework of their current contract with NICE, Warwick Evidence has been allocated the following projects:

Project number
Project title
Principal Investigator
Start date
13/65

ChondroCelect for cartilage defects of the knee [ID686]

Norman Waugh / Hema Mistry 01/06/15
13/74 Multiple sclerosis - beta interferon and glatiramer acetate (review of TA32) [ID809] G J Melendez-Torres 05/01/16
14/206/11 Lesinurad in combination with a xanthine oxidase inhibitor for previously treated chronic hyperuricaemia in gout [ID761] James Mason 28/01/16
15/69/07 Ramucirumab with docetaxel after platinum chemotherapy for treating metastatic, non small cell lung cancer [ID838] Aileen Clarke 18/12/15
15/69/06 Daclizumab for treating relapsing-remitting multiple sclerosis Aileen Clarke 05/04/16
15/17/03 xTAG Gastrointestinal Pathogen Panel for the detection and identification of pathogens in gastroenteritis James Mason 04/12/15
16/56/22 Ocrelizumab for treating primary progressive multiple sclerosis [ID938] G. J. Melendez-Torres 26/06/17
15/148/09 Dapagliflozin in triple therapy regimens for treating type 2 diabetes [ID962] Norman Waugh 09/03/16
16/10/03

Biotin for primary and secondary progressive multiple sclerosis [ID919]

G J Melendez-Torres 02/12/16
16/10/11

Venetoclax for treating chronic lymphocytic leukaemia associated with a 17p deletion or TP53 mutation [ID944]

Hema Mistry

08/08/16
14/189/02 Dimethyl fumarate for treating moderate to severe plaque psoriasis (ID776) James Mason 03/11/16
16/54/01 Glycerol phenylbutyrate for treating urea cycle disorders [ID942] Aileen Clarke 13/10/2016
16/54/06 Recombinant human nerve growth factor for treating neurotrophic keratitis ID946 Aileen Clarke 18/01/2017
16/30/04 Faecal calprotectin testing to monitor response to pharmacological treatment in patients with inflammatory bowel disease Hema Mistry 21/02/17

Please find a selection of completed projects for NICE / NIHR here.


Research projects conducted with other external funding

The researchers of Warwick Evidence also successfully apply for additional funding. Currently, the team works on the following projects:

Project Title
Funding Body
Value
Date
Investigators
ICARE4EU (Innovating care for people with multiple chronic conditions in Europe) DG SANCO Second Public Health Programme £ 30.000 2013-2016 Dyakova, M, and Clarke, A
Improving health outcome
for young people with long term conditions: the role of digital communication
in current and future patient-clinician communication for NHS providers of
specialist clinical services (the LYNCs study)
NIHR: Health Services and Delivery Research Programme   05.2014 - 02.2017 Griffiths F, Stuart J, Cave
J, Madan J, Sutcliffe P et al.
CLAHRC: Theme 3: Prevention and Detection NIHR £1,250,000 2014-2018 Clarke, A
Chronic Headache Education and Self-management Study (CHESS). NIHR Programme Grants for Applied Research £1,989,949 60 months from 05/01/2015 Underwood M, Mistry H.
Epidemiology of Communicable Disease Control Evidence Centre PHE £600,000 2015-2020 Clarke A
LDC Staff Network Funding: Qualitative and Mixed Methods Interest Group Warwick University Learning and Development Centre £875.00 Oct 2015 – Oct 2016 Grove A, Tierney S, Johnson R
Development of a UK Evidence-Based Pathway for the Management of Chronic Constipation in Adults NIHR PGfAR £1,950,294 2013-2018 (60 months), Knowles C, Emmanuel A, Vaizey C, Norton C, Gilbert D, Mason J, Sedgwick J, Cardozo L, Moss-Morris R, Scott M, Eldridge S, Taylor S, Yiannakou Y, Smalley L.
Improving the diagnosis and management of dementias of lewy body type in the NHS (DIAMAND-Lewy) NIHR Programme Grant £1,660,753 2013 – 2017 (60 months) Brien J, Burn D, Thomas A, Bamford C, McKeith I, Taylor J, Allan L, James P, Deverill M, Finch T, Mason J, Docking
How can interventions integrating health and academic education in schools help prevent substance misuse and violence, and reduce health inequalities among young people? Systematic review and evidence synthesis NIHR Evaluation, Trials and Studies £217,442 Jan 2016 – March 2018 Bonell C (PI), Thomas J, Fletcher A, Campbell R, Melendez-Torres GJ
A Prospective Pilot Study of Home Monitoring in Adults with Cystic Fibrosis (HOME-CF). NIHR Research for Patient Benefit £275,025 January 2016 for 27 months Nash E, Mistry H
Acute Kidney Outreach to Reduce Deterioration and Death (AKORDD) - A pilot study to look at enhancing patient care improving patient outcomes and reducing NHS Costs. NIHR Research for Patient Benefit. £249,910 April 2015 for 30 months Thomas M, Mistry H
Bibliometric study of macular research in the UK Macular Society £5,000 2016 Waugh N, Royle P
PEARL. Early Laser Treatment for Diabetic Eye Disease in China: A Pilot Randomized Trial MRC Newton Programme. Trial Development Grant scheme of the Global Trials Initiative £150,000 24 months from 01/09/2016 Congdon N, Lois N, Waugh N, Mistry H
Diabetic Macular Oedema and Diode Subthreshold micropulse laser (DIAMONDS). NIHR Health Technology Assessment £1,004,147 50 months from 01/04/2016 Lois N, Waugh N, Mistry H
         

Please find a list of selected completed research projects here.