Eligibility Criteria
Inclusion Criteria:
- Women, age >18 years
- Histologically confirmed invasive or non-invasive primary breast cancer scheduled for surgical excision
- Considered high risk of developing shoulder problems after surgery defined by one or more of the following:
- planned axillary node clearance (ANC);
- planned radiotherapy (RT);
- existing shoulder problems (based upon PROSPER screening criteria);
- obesity defined as BMI (greater than or equal to) >30;
- any subsequent axillary surgery related to primary surgery, e.g. ANC conducted after sentinel lymph node biopsy (SLNB)
- Willing and able to comply with the protocol
- Written informed consent
- Any later decision (made within 6 weeks of surgery) to refer to RT
Note:
- Women who have had previous breast surgery (e.g. excision of benign tumour or breast cyst) are eligible for invitation;
- Women who have had previous contralateral (opposite side) mastectomy are eligible for invitation.
Exclusion Criteria
- Males
- Women having immediate reconstructive surgery
- Women having SLNB with or without breast surgery unless have other high risk criteria
- Women having bilateral breast surgery
- Evidence of known metastatic disease at time of recruitment
This information is taken from Version 1.0 of the PROSPER Protocol (dated 01 Jun 2015)
Contact the Trial Office:
Please direct all general enquiries to:
prosper at warwick dot ac dot uk