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Trials in set up

scientist using microscope

WCTU's team is leading on a wide range of trials with the aim of informing modern clinical and health care practice. Spanning a range of major health issues, learn more about our work.

Trials in set up

Trial name About the Trial Trial type Chief Investigator
Awake ProneLink opens in a new window Awake Prone positioning in patients with acute hypoxaemic respiratory failure not due to COVID-19 Emergency and Critical Care group Dr Keith Couper
BigTOE Big Toe OstEoarthritis Trial: Inserts (BigTOE Inserts) Surgery, pain and rehabilitation

Associate Professor Michael Backhouse


The Confederation of Respiratory Critical Care Trials (CoReCCT) Emergency and Critical Care  


Neurally Adjusted Ventilatory Assist (NAVA) compared to conventional ventilation for patients at risk of difficult or prolonged weaning from invasive mechanical ventilation: The UK NAVA Trial Emergency and Critical Care

Dr Daniel Hadfield

PROTECT Airways The clinical and cost effectiveness of advanced airways protection device versus conventional endotracheal tubes in Intensive care unit patients requiring mechanical ventilation: a multicentre, pragmatic randomised clinical trial (PROTECT Airways) Emergency and Critical Care

Dr Gareth Kitchen

RELEASE Airway Pressure Release Ventilation (APRV) vs conventional ventilation for patients with moderate to severe acute hypoxemic respiratory failure (RELEASE). Emergency and Critical Care

Prof Luigi Camporota

Prof Danny McAuley