Skip to main content Skip to navigation

Information for Health Professionals

Information for Health Professionals:

The METEOR2 is a study for people who have had some meniscus removed from their knee, don’t have diagnosed arthritis of the knee but still have pain more than 6 months afterwards.

Tears of the meniscus are common and can occur following traumatic injuries or from degenerative tears, which occur over time. Tears of the meniscus are often treated by an operation called a meniscectomy. After this operation, most people's pain and symptoms improve over time. For some people, the pain and symptoms get worse.


METEOR2 is looking for people who have:

  1. Have been treated by having meniscus removed at least 6 months previously.
  2. Are still experiencing pain or other symptoms.

To be eligible for the study, patients cannot have arthritis of the knee.

Two possible treatment options for these types of patients are:

Personalised Knee Therapy

Meniscal Transplant

Personalised knee therapy (physiotherapy, sometimes bracing, advice on work or activities and how to improve pain; may also be known as optimised rehabilitation).

An operation to insert a replacement meniscus taken from someone who has died, this is known as a 'meniscal transplant'.

We do not know whether this problem is best treated with personalised knee therapy or surgery to replace the meniscus. Both treatments could improve pain and restrictions.

METEOR2 aims to find out which of these treatments is best. Participants will be randomly allocated to either treatment and we will follow up on their recovery progress. We plan to recruit 144 participants from hospitals across the UK and internationally, including Australia, Canada and Belgium.

  • Referrals for UK based patients:

If you think you may have a patient who may be eligible for the study and would like to take part, please refer the patient to one of our participating sites as stated on the right hand side.


Chief Investigator: Prof Andrew Metcalfe & Prof Timothy Spalding

UK Study Team Email:

Australia Study Team Email: opens in a new window

Hospitals open to recruitment:


  • Musgrave Park Hospital - Belfast
  • Southmead Hospital - Bristol
  • Addenbrooke's Hospital - Cambridge
  • Rotherham General Hospital
  • University Hospital Coventry & Warwickshire
  • University Hospital College London
  • Royal National Orthopaedic
  • Lanarkshire University Hospitals
  • Nuffield Orthopaedic Centre - Oxford
  • Gloucester Royal Hospital
  • Wrightington Hospital
  • Royal Devon & Exeter
  • The Royal Orthopaedic, Birmingham
  • Queen Elizabeth University Hospital - Glasgow


  • Royal North Shore Hospital
  • North Shore Private Hospital
  • Brisbane Private Hospital