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Antimicrobial Screening Facility

Antimicrobial Screening Facility

Toxicity

Antimicrobial Susceptibility Testing

  • Use of BSL1 and BSL2 pathogens
  • Bacterial and fungal pathogens
  • Minimum Inhibitory Concentration
  • Minimum Bactericidal Concentration
  • Minimum Biofilm Eradication Concentration
  • Checkerboard Synergy
  • Disk Diffusion
  • Time-kill
  • Post-Antimicrobial Effect
  • E-test
  • DNA/RNA extraction

Robot

High-throughput screening: MIC hit detection

We can provide high-throughput hit screening of your compound library for both BSL1 and BSL2 pathogens

  • We have previously worked with libraries of up to 2000 compounds
  • Test both bacterial and fungal pathogens
  • Providing fast and reliable antimicrobial screening
  • Our scientists can help you design high-throughput protocols for your bespoke application.

Get in touch to find out more!

Get the help you need

Resistance

Structural biology services

  • Structural biology: X-ray crystallography, small angle X-ray scattering (SAXS), analysis of protein-ligand interactions.
  • Protein production: cloning, expression and purification.
  • Wide range of biochemical and biophysical assays for activity and binding measurements.

Pig bronchiole with bacterial biofilm

Biofilm and Infection Models

We provide a number of different biofilm models which can help reflect the treatment of chronic infections

    • Test against BSL1 and BSL2 bacteria or fungi
    • High or mid throughput options
    • Specialised infection models

    More detailsLink opens in a new window

    Mode of Action

    Coming soon - Virology Screening

    • ISO 21702: Measurement of antiviral activity on plastics and other non-porous surfaces.
    • Various viruses available
    • Various cell lines available
    • Various molecular detection services
    • Many other virology services available.

    GenomicsLink opens in a new window

    The AMR facility can provide DNA/RNA extraction and then sequencing can be provided by the genomics facility.

    • Next Generation Sequencing
    • Sanger Sequencing
    • Microarrays
    • Real time PCR

    Warwick Scientific Services

    • See what else Warwick has available
    • World-class analytical support
    • Custom synthesis
    • Work bespoke to your needs

     

    https://warwick.ac.uk/wss

    Resistance Generation

    • Sub-MIC Selection
    • Mutation Rate Calculations
    • Resistant mutants
    • Genomic Sequencing