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Optimising Anthocyanin Recovery from Food Waste for metabolic health solutions
Secondary Supervisor(s): Dr Helen Onyeaka
University of Registration: University of Birmingham
BBSRC Research Themes:
Project Outline
Overview:
This interdisciplinary project integrates biotechnology, food science, and sustainability to valorise grape skins and berry pomace, which are agri-food by-products rich in anthocyanins. We will optimise anthocyanin extraction using enzyme-assisted and ultrasound methods, benchmarking against conventional ethanol extraction. Extracts will be characterised (TAC, HPLC, antioxidant capacity) and incorporated into two model food matrices (yoghurt and baked product) representing dairy and bakery systems.
Innovation & Impact:
We hypothesise that combining enzyme pre-treatment with low-solvent ultrasound extraction enhances recovery of acylated anthocyanins, improves post-digestion stability, and boosts bioactivity (glucose uptake, lipid reduction) in adipocyte and hepatocyte models. A cradle-to-gate life-cycle assessment (LCA) will quantify environmental benefits, supporting a circular bioeconomy approach.
Objectives and Milestones:
1. Extraction Efficiency (M1–M9): ≥25% higher TAC yield vs ethanol; ≤5 L/kg solvent use.
2. Profile Quality (M1–M12): ≥60% retention of acylated anthocyanins post-processing.
3. Food Matrix Performance (M13–M18): ≥50% anthocyanin retention post-digestion; sensory score ≥6/9.
4. Cellular Bioactivity (M19–M24): ≥20% increase in glucose uptake; ≥20% reduction in lipid accumulation; no cytotoxicity.
5. Sustainability Assessment (M25–M30): ≥30% GHG reduction vs control via LCA.
Training and Relevance:
This project aligns with MIBTP’s focus on interdisciplinary bioscience, offering training in analytical chemistry, food formulation, cell biology, and environmental modelling. It supports sustainable innovation in functional foods and provides preclinical evidence for industry adoption.