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Professor Andrew Devitt

Supervisor Details

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Contact Details

Professor Andrew Devitt

School of Biosciences, Aston University

Research Interests

As an inflammatory cell biologist, my research over 20 years has focused on the innate immune system and its role in protection and tissue repair through the study of phagocyte clearance of dying (apoptotic) cells and microbial challenge. Research within my research group addresses membrane receptors/ligands and cell communication in this phagocytic clearance process. Current work aims to define the mechanisms by which apoptotic cells communicate via extracellular vesicles (EV). This BBSRC-funded work is revealing novel EV structure-function relationships that underpin tissue repair and regeneration capacity of EV from both apoptotic and viable cells, including mesenchymal stem cells. This research has introduced the concept that EV are an active extracellular metabolic compartment capable of modulating inflammation. The ultimate aim of my group’s research is to modify inflammation for therapeutic gain either through the inhibition of inflammation (e.g. in cardiovascular disease and regenerative medicine applications) or promoting inflammation (e.g. in tumours).


MIBTP Project Details

Previous Projects (2024-25)

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Previous Projects (2023-24)

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