Dr Ben Warren
Supervisor Details
Research Interests
My fascination with sensory neuroscience was forged during my observations of swarming mosquitoes during my undergraduate degree. The female mosquito’s high-pitched whine (all too familiar to victims of their bites) turns out to be necessary for male mosquitoes to locate them. The remarkable auditory sensitivity of mosquitoes is underpinned by ~16,000 neurons, jam-packed into a tiny structure the size of a pin-head. My imagination was captured by these mechanosensory neurons and sparked a question which has guided my research journey ever since: How do insect auditory neurons convert sound-induced nanometre displacements into electrical signals that the insect can hear?
To pursue this question I migrated to the renowned Kloppenburg lab in Cologne to learn the art of patch-clamping: a powerful electrophysiological tool for understanding the inner electrical workings of neurons. I gained further experience in the world-famous Göpfert lab in Göttingen which utilised the fruit fly to understand the molecular basis of mechanotransduction.
Studies of auditory neurons in insects were hampered by a lack of electrical recordings of the fundamental mechanical-to-electrical step. To address this gap in knowledge I turned to the locust, which has large accessible auditory neurons, which I brought the powerful patch-clamp technique to bear. In the thriving neuroscience community at Leicester, and within the specialist Locust Labs (headed by Drs Tom Matheson and Swidbert Ott), I pioneered the first patch-clamp recordings from insect (locust) auditory neurons. I now use the locust ear as a model system to understand basic principles of auditory transduction that apply across animals.
Scientific Inspiration
Will Hunting (Fictional character from the film Good Will Hunting) – Because he was driven by his intellectual curiosity, was never intimidated by those above him and he liked apples.
MIBTP Project Details
Previous Projects (2024-25)
Primary supervisor for:
Co-supervisor on a project with Dr Roberto Feuda.
Previous Projects (2023-24)
Primary supervisor for: