Professor Corinne Spickett
Supervisor Details
Research Interests
My research is centred in the field of Redox Biology and Oxidative Stress, and I am an internationally recognized researcher in this field. Redox balance controls many cell signaling pathways leading to cell proliferation, differentiation and toxicity. I am particularly well-known for research on analysis of oxidized phospholipids using mass spectrometry, and recently this has expanded into lipidomics and ox-lipidomics. My group also works on analysis and biological effects of protein oxidation both in vitro and in vivo. A strong current focus is on the structure-function relationship of protein lipoxidation, which involves the formation of adducts of oxidative lipids with proteins, which is important in many inflammatory diseases and cancer.
I led the Horizon 2020 Innovative training network MASSTRPLAN (Mass Spectrometry Training network in Protein Lipid Adduct Analysis) from 2015 to 2019. More information is available on our webpage https://www.masstrplan.org/. I am also a member of AMPL (Aston Membrane Proteins and Lipids group) and a Co-investigator on the international collaborative projects MemBrane and MemTrain, where my role involves support for lipidomic and ox-lipidomic analysis.
Scientific Inspiration
Professor Mike Murphy, MRC Mitochondrial Biology Unit – he does fantastic fundamental science on redox stress in mitochondria that has broad biomedical implications while being amazingly unassuming (as well as funny).
Research Groups
MIBTP Project Details
Current Projects (2025-26)
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Co-supervisor on a project with Dr Benjamin Lane.
Previous Projects (2024-25)
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Co-supervisor on a project with Dr Rebecca Jones.
Previous Projects (2023-24)
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